Research Areas
Protein Kinase and Plant Stress Biology
Education
Ph.D. in Plant Biology, Henan University, 2010
M.S. in Plant Biology, Henan University, 2003
B.S. in Biology, Henan University, 2000
Experience
Work Experience
2017- Present: Principal Investigator, Shanghai Center for Plant Stress Biology
2011-2016: Postdoctoral Research Associate, Purdue University, West Lafayette, USA
2010-2011: Assistant Professor, Henan University
2003-2005: Research Assistant, Henan University
Publications
1. Pengcheng Wang. et al. Mol. Cell. 2018 Jan 4;69(1):100-112.e6. doi: 10.1016/j.molcel.
2. Jun Yan. et al. PLoS Genetics 2017, 13(4): e1006753.
3. Zhao C. et al. Dev. Cell. 2017 Dec 4;43(5):618-629.e5. doi: 10.1016/j.devcel.
4. Chuan-Chih Hsu. et al. J Am Soc Mass Spectrom. 2017 Jun;28(6):1127-1135. doi: 10.1007/s13361-017-1603-5. Epub 2017 Mar 10.
5. Yueh-Ju Hou. et al. PLOS Genetics 2016, 12: e1005835.
6. Yang Zhao. et al. Proc. Natl. Acad. Sci. USA 2016, 113: 1949-1954
7. Pengcheng Wang. et al. Proc. Natl. Acad. Sci. USA 2015, 112: 613-618
8. Xiangqiang Zhan. et al. Nature Commun. 2015, 6: 8139
9 Cheng-Guo Duan, . et al. EMBO J. 2015, 34: 581–592
10. Pengcheng Wang. et al. Plant Signaling & Behavior 2015, 10(6): e1031939.
11. Ying Zhang. et al. Dev. Cell 2015, 33: 136–149
12. Liang Xue. et al. Molecular & Cellular Proteomics 2014, 13: 3199-3210
13 Yingfang Zhu. et al. Plant Cell 2014, 26: 4149-4170
14. Yang Zhao. et al. Science Signal. 2014, 7(328): ra53
15. Huiming Zhang. et al. Mol. Cell 2014, 54: 418-430
Research Interests
Eukaryotic protein kinases are major regulatory components in all cellular functions. By adding phosphate groups to substrate proteins, they direct the activity, localization, association with other proteins, and overall function of many proteins and serve to orchestrate the activity of almost all cellular processes. Compare to other eukaryotes, flowering plants have more genes encoding protein kinases in their genomes. In the model plant Arabidopsis, more than 1000 protein kinases and 20,000 phosphosites have been identified (unpublished data), suggested the critical functions of protein kinase and their substrates in plants. Despite the importance of phosphorylation-dependent signaling to cellular physiology, a comprehensive understanding of the phosphorylation networks and pathways governing cell signaling in plant is still lacking. We will use cutting-edge phosphoproteomics to identify the substrate of the important protein kinases in abiotic stress responses and build up the protein kinase-substrate networks in plants. By biochemical, genetic, and physiological approaches, we aim to identify novel components in abiotic stress signaling pathways and to improve stress tolerance in agriculture crops using the novel biological discoveries.
Students
现指导学生
桑田 硕士研究生 071007-遗传学
杨帆 博士研究生
王艺 博士研究生
蔺祯 硕士研究生
赵莎莎 硕士研究生
朱晨 硕士研究生