Application and biological effects of rare earth elements, ecotoxicology of manufactured nanomaterials

1994.07-1997.09  Ph.D. in Radiochemistry, Peking University, Beijing, China.

1991.09-1994.07  M.Sc. in Inorganic Chemistry, Beijing Normal University, China.

1987.09-1991.07  B. Sc. in Chemistry, Beijing Normal University, China

   

1999.10 –present  Assistant professor (1999), Associate Professor (2000), Full Professor (2006), Multidisciplinary Research Center, Institute of High Energy Physics, The Chinese Academy of Sciences.

1997.9- 1999.9   Postdoctoral Fellow, Institute of High Energy Physics, The Chinese Academy of Sciences.

2016.03-present   Nuclear Analytical Techniques: basis and method

2019, China Academy of Sciences Distinguished Scientific Achievement Award (Research Division of Biomedical Effects of Nanomaterials and Nanosafety)

2016, Breakthrough Prize in Fundamental Physics (Daya Bay Cooperation)

2015, Second Prize of Science and Technology Award of Beijing

2013, Outstanding Research Award from Chinese Nuclear Society

2009, Shanghai Natural Science Award from Shanghai Association for Science and Technology

2007, Outstanding Research Award from Institute of High Energy Physics, CAS

2004, Shanghai Science and Technology Progress Award, Shanghai Association for Science and Technology

1. Ma Y, Xie C, He X, Zhang B, Yang J, Sun M, Luo W, Feng S, Zhang J, Wang G, Zhang Z*. Effects of Ceria Nanoparticles and CeCl3 on Plant Growth, Biological and Physiological Parameters, and Nutritional Value of Soil Grown Common Bean (Phaseolus vulgaris). Small, 2020, DOI: 10.1002/smll.201907435.

2. Guo ZL, Luo YL, Zhang P, Chetwynd AJ, Xie HQ, Monikh FA, Tao WQ, Xie CJ, Liu YY, Xu L, Zhang ZY, Valsami-Jones E, Lynch I, Zhao B. Deciphering the particle specific effects on metabolism in rat liver and plasma from ZnO nanoparticles versus ionic Zn exposure. Environ Int, 2020, 136: 105437

3. Zhang Peng*, Guo Zhiling, Lynch Iseult, Luo Wenhe, Monikh Fazel Abdolahpur, Xie Changjian, Valsami-Jones Eugenia, Zhang Zhiyong*. Graphene Oxide Induced Iron Overload and Subsequent Oxidative Damage in Rice (Oryza. sativa L.): A New Mechanism of Nanomaterial Phytotoxicity. Environ Sci Technol, 2020, DOI: 10.1021/acs.est.9b05794

4. Ding YY, Liu MC, Zhao J, Yan WQ, Wei LH, Zhang ZY, Wen LJ. Co-precipitation approach to measure amount of 238U in copper to sub-ppt level using ICP-MS. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2019, 941: 162335

5. Liu M, Feng S, Ma Y*, Xie C, He X, Ding Y, Zhang J, Luo W, Zheng L, Chen D, Yang F*, Chai Z, Zhao Y, Zhang Z*. Influence of Surface Charge on the Phytotoxicity, Transformation, and Translocation of CeO2 Nanoparticles in Cucumber Plants. ACS Appl Mater Interfaces. 2019, 11: 16905-16913. doi: 10.1021/acsami.9b01627

6. Xie C, Ma Y, Yang J, Zhang B, Luo W, Feng S, Zhang J, Wang G, He X, Zhang Z. Effects of foliar applications of ceria nanoparticles and CeCl3 on common bean (Phaseolus vulgaris). Environ Pollut. 2019, 250: 530-536. doi: 10.1016/j.envpol.2019.04.042

7. Zhang JZ, Ma YH, Yang WJ, Xue JQ, Ding YY, Xie CJ, Luo WH, Gao FP, Zhang ZY, Zhao YL, Chai ZF, He X*, Comparison study on core-and surface-radiolabeling strategies for the assembly of iron oxide nanoparticles based theranostic nanocomposites. Nanoscale, 2019, 11: 5909-5913

8. He XX, Xie CJ, Ma YH*, Wang L, He X, Shi WQ, Liu XD, Liu Y*, Zhang ZY*. Size-dependent toxicity of ThO2 nanoparticles to green algae Chlorella pyrenoidosa. Aquat Toxicol, 2019, 209: 113-120.

9. Xie CJ, Zhang JZ, Ma YH, Ding YY, Zhang P, Zheng LR, Chai ZF, Zhao YL, Zhang ZY*, He X*.. Bacillus subtilis Causes Dissolution of Ceria Nanoparticles at the Nano-Bio Interface. Environ Sci: Nano, 2019, 6, 216-223. DOI: 10.1039/C8EN01002A

10. Zhang P, Ma YH, Xie CJ, Guo ZL, He X, Valsami-Jones E, Lynch I, Luo WH, Zheng LR, Zhang ZY*. Plant Species Dependent Transformation and Translocation of Ceria Nanoparticles. Environ Sci: Nano, 2019, 6, 60-67. DOI: 10.1039/C8EN01089G

11. Xiao LN, Wu ZR, Zhang JZ, Wang GH, Ma YH, Ding YY, He X*, Zhang SQ*, Zhang ZY*. Synthesis, Photothermal Effect and Cytotoxicity of Fe3O4@Au Nanocomposites. J Nanosci Nanotechnol, 2019, 19: 2467-2473. 

12. Wu JJ, Ma YH, Ding YY, Zhang P, He X *, Zhang ZY*.Toxicity of Two Different Size Ceria Nanoparticles to Mice After Repeated Intranasal Instillation. J Nanosci Nanotechnol, 2019, 19: 2474-2482

13. F.P. An, et al., (Daya Bay Collaboration), Extraction of the U-235 and Pu-239 Antineutrino Spectra at Daya Bay, Phys. Rev Lett., 123, 111801 (2019)

14. F.P. An, et al., (Daya Bay Collaboration), Improved measurement of the reactor antineutrino flux at Daya Bay, Phys. Rev D, 100, 052004 (2019)

15. 冯盛, 马宇辉, 杨芳, 张智勇. 不同表面电荷的纳米CeO2的合成及表征. 中国稀土学报 2019, 37: 193-198

16. Ma Y, Yao Y, Yang J, He X, Ding Y, Zhang P, Zhang J, Wang G, Xie C, Luo W, Zhang J, Zheng L, Chai Z, Zhao Y, Zhang Z*. Trophic Transfer and Transformation of CeO2 Nanoparticles along a Terrestrial Food Chain: Influence of Exposure Routes. Environ Sci Technol, 2018, 52(14): 7921-7927.

17. Li Y, Li H, Li YF, Zhao J, Guo J, Wang R, Li B, Zhang Z, Gao Y. Evidence for molecular antagonistic mechanism between mercury and selenium in rice (Oryza sativa L.): A combined study using 1, 2-dimensional electrophoresis and SR-XRF techniques. J Trace Elem Med Biol, 2018, 50: 435-440

18. Wang H, Liu X, Zhao J, Yue Q, Yan Y, Gao Z, Dong Y, Zhang Z, Fan Y, Tian J, Wu N, Gong Y. Crystal structures of multicopper oxidase CueO G304K mutant: structural basis of the increased laccase activity. Sci Rep, 2018, 8: 14252

19. Alexandre Konate, Xiao He, Peng Zhang, Yuhui Ma, Jie Yang, Gibson Alugongo, Yukui Rui, Zhiyong Zhang. Alleviation of cadmium-induced changes on growth, antioxidative enzyme activities and lipid peroxidation in crop seedings by magnetic (Fe3O4) nanoparticles. Fresenius Environmental Bulletin, 2018, 27(6): 3920-3935

20. Alexandre Konate, Yaoyao Wang, Xiao He, Muhammd Adeel, Peng Zhang, Yuhui Ma, Yayun Ding, Junzhe Zhang, Jie Yang, Simon Kizito, Yukui Rui, Zhiyong Zhang. Comparative effects of nano and bulk-Fe3O4 on the growth of cucumber (Cucumis sativus). Ecotoxicology and Environmental Safety, 2018, 165: 547-554, DOI: 10.1016/j.ecoenv.2018.09.053

21. F.P. An, et al., (Daya Bay Collaboration), Cosmogenic neutron production at Daya Bay, Physical Review D 97, 052009 (2018)

22. F.P. An, et al., (Daya Bay Collaboration), Seasonal variation of the underground cosmic muon flux observed at Daya Bay, JCAP 01(2018)001

23. Ma YH, He X, Zhang P, Zhang ZY, Ding YY, Zhang JZ, Wang GH, Xie CJ, Luo WH, Zhang J, Zheng LR, Chai ZF, Yang K. Xylem and phloem based transport of CeO2 nanoparticles in hydroponic cucumber plants. Environ Sci Technol, 2017, 51, 5215-5221

24. Zhang P, Xie CJ, Ma YH, He X, Zhang ZY, Ding YY, Zheng LR, Zhang J. Shape-dependent transformation and translocation of ceria nanoparticles in cucumber plants. Environ Sci Technol Lett, 2017, 4 (9): 380–385

25. Peng C, Ma YH, Ding YY, He X, Zhang P, Lan T, Wang DQ, Zhang ZH, Zhang ZY. Influence of Speciation of Thorium on Toxic Effects to Green Algae Chlorella pyrenoidosa, Int J Mol Sci, 2017, 18, 795

26. Konate A, He X, Zhang ZY, Ma YH, Zhang P, Alugongo GM, Rui YK. Magnetic (Fe3O4) Nanoparticles Reduce Heavy Metals Uptake and Mitigate Their Toxicity in Wheat Seedling. Sustainability, 2017, 9(5): 790

27. Zhang P, Ma Y, Liu S, Wang G, Zhang J, He X, Zhang J, Rui Y, Zhang Z. Phytotoxicity, uptake and transformation of nano-CeO2 in sand cultured romaine lettuce. Environ Pollut., 2017, 220 (Pt B): 1400-1408 doi: 10.1016/j.envpol.2016.10.094

28. Guo ZL, Xie CJ, Zhang P, Zhang JZ, Wang GH, He X, Ma YH, Zhao B, Zhang ZY. Toxicity and transformation of graphene oxide and reduced graphene oxide in bacteria biofilm. Sci Total Environ, 2017, 580: 1300-1308

29. Wang GH, Ma YH, Zhang P, He X, Zhang ZH, Qu MH, Ding YY, Zhang JZ, Xie CJ, Luo WH, Zhang J, Chu SQ, Chai ZF, Zhang ZY. Influence of phosphate on phytotoxicity of ceria nanoparticles in an agar medium. Environ Pollut., 2017, 224:392-399 http://dx.doi.org/10.1016/j.envpol.2017.02.019

30. Gui X, Rui M, Song Y, Ma Y, Rui Y, Zhang P, He X, Li Y, Zhang Z, Liu L. Phytotoxicity of CeO2 nanoparticles on radish plant (Raphanus sativus). Environ Sci Pollut Res Int, 2017, 24(15): 13775-13781

31. F. P. An, et al., (Daya Bay Collaboration), Improved measurement of the reactor antineutrino flux and spectrum at Daya Bay, Chinese Physics C, 2017, 41(1): 013002

32. F. P. An, et al., (Daya Bay Collaboration), Measurement of electron antineutrino oscillation based on 1230 days of operation of the Daya Bay experiment, Phys. Rev. D 2017, 95: 072006

33. F. P. An, et al., (Daya Bay Collaboration), Evolution of the reactor antineutrino flux and spectrum at Daya Bay, PRL, 2017, 118: 251801 

34. Cai HT, Ma YH, Wu ZR, Ding YY, Zhang P, He X, Zhou JR, Chai ZF, Zhang ZY. Protein corona influences liver accumulation and hepatotoxicity of gold nanorods. NanoImpact, 2016, 3-4: 40-46

35. Ma YH, Wang JK, Peng C, Ding YY, He X, Zhang P, Li N, Lan T, Wang DQ, Zhang ZH, Sun FH, Liao HQ, Zhang ZY. Toxicity of cerium and thorium on Daphnia magna. Ecotoxicol Environ Saf, 2016, 134: 226-232 DOI: 10.1016/j.envpol.2016.10.094

36. Daya Bay Collaboration; MINOS Collaboration. Limits on Active to Sterile Neutrino Oscillations from Disappearance Searches in the MINOS, Daya Bay, and Bugey-3 Experiments. PRL, 2016, 117(15): 151801

37. Daya Bay Collaboration. Improved Search for a Light Sterile Neutrino with the Full Configuration of the Daya Bay Experiment. 2016, 117(15): 151802

38. Daya Bay Collaboration. New measurement of q13 via neutron capture on hydrogen at Daya Bay. PRD, 2016, 93, 072011 

39. Daya Bay Collaboration. Measurement of the Reactor Antineutrino Flux and Spectrum at Daya Bay, PRL 116, 061801 (2016)

40. Daya Bay Collaboration. The detector system of the Daya Bay reactor neutrino experiment, NIMA, 811 (2016) 133–161

41. Ma YH, Zhang P, Zhang ZY*, He X, Zhang JZ, Ding YY, Zhang J, Zheng LR, Guo Z, Zhang LJ, Chai ZF, Zhao YL. Where does the transformation of precipitated ceria nanoparticles in hydroponic plants take place? Environ Sci Technol, 2015. 49(17): 10667-10674 DOI: 10.1021/acs.est.5b02761

42. Zhang JZ, He X, Zhang P, Ma YH, Ding YY, Wang ZY, Zhang ZY*. Quantifying the dissolution of nanomaterials at the nano-bio interface. Sci China Chem, 2015, 58(5): 761-767

43. Li YY, He X*, Yin JJ, Zhang P, Ma YH, Li JY, Zhang J, Zhao YL, Chai ZF, Zhang ZY*. Acquired superoxide-scavenging ability of ceria nanoparticles. Angew Chem Int Ed, 2015, 54: 1832–1835 DOI: 10.1002/anie.201410398

44. He X, Pan YY, Zhang JZ, Li YY, Ma YH, Zhang P, Ding YY, Zhang J, Wu ZQ*, Zhao YL, Chai ZF, Zhang ZY*. Quantifying the total ionic release from nanoparticles after particle-cell contact. Environ Pollut, 2015, 196: 194-200  DOI: j.envpol.2014.09.021

45. Rui YK#*, Zhang P#, Zhang YB, Ma YH, He X, Gui X, Li YY, Zhang J, Zheng LR, Chu SQ, Guo Z, Chai ZF, Zhao YL, Zhang ZY*. Transformation of ceria nanoparticles in cucumber plants is influenced by phosphate. Environ Pollut, 2015, 198: 8-14. DOI: 10.1016/j.envpol.2014.12.017

46. Gui X, He X*, Ma YH, Zhang P, Li YY, Ding YY, Yang K, Li HF, Rui YK*, Chai ZF, Zhao YL, Zhang ZY*. Quantifying the distribution of ceria nanoparticles in cucumber roots: the influence of labeling. RSC Adv, 2015, 5: 4554-4560

47. Gui X, Zhang Z, Liu S, Ma Y, Zhang P, He X, Li Y, Zhang J, Li H, Rui Y, Liu L, Cao W. Fate and Phytotoxicity of CeO2 Nanoparticles on Lettuce Cultured in the Potting Soil Environment. PLoS One, 2015, 10(8):e0134261. doi: 10.1371/journal.pone.0134261

48. Zhang P, Ma YH, Zhang ZY*, He X, Li YY, Zhang J, Zheng LR, Zhao YL. Species-specific toxicity of ceria nanoparticles to Lactuca plants. Nanotoxicology, 2015, 9(1): 1–8 DOI:10.3109/17435390.2013.855829

49. Ma Y, Zhang P, Zhang Z*, He X, Li Y, Zhang J, Zheng L, Zhao Y, and Chai Z. Origin of the different phytotoxicity and biotransformation of cerium and lanthanum oxide nanoparticles in cucumber. Nanotoxicology, 2015, 9(2): 262-270 DOI:10.3109/17435390.2014.921344

50. Zhang ZY*, He X, Ma YH, Ding YY, Chai ZF. New Nuclear Facilities and Their Analytical Applications in China. Radiochim Acta, 2014, 102 (1-2): 3-11 DOI 10.1515/ract-2014-2098

51. Peng L, He X, Zhang P, Zhang J, Li YY, Zhang JZ, Ma YH, Ding YY, Wu ZQ*, Chai ZF, Zhang ZY*. Comparative pulmonary toxicity of two ceria nanoparticles with the same primary size. Int J Mol Sci, 2014, 15, 6072-6085; doi:10.3390/ijms15046072.

52. Wanda Beriguete, Jun Cao, Yayun Ding, Sunej Hans, Karsten M. Heeger, Liangming Hu, Aizhong Huang, Kam-Biu Luk, Igor Nemchenok, Ming Qi, Richard Rosero, Hansheng Sun, Ruiguang Wang, Yifang Wang, Liangjian Wen, Yi Yang, Minfang Yeh, Zhiyong Zhang, Li Zhou. Production of a gadolinium-loaded liquid scintillator for the Daya Bay reactor neutrino experiment. Nucl Instrum Meth A, 2014, 763: 82-88  DOI: 10.1016/j.nima.2014.05.119

53. Cui D, Zhang P, Ma YH, He X, Li YY, Zhao YC*, Zhang ZY*. Phytotoxicity of silver nanoparticles to cucumber (Cucumis sativus) and wheat (Triticum aestivum). J Zhejiang Univ Sci A, 2014, 15(8): 662-670

54. Cui D, Zhang P, Ma YH, He X, Li YY, Zhang J, Zhao YC*, Zhang ZY*. Effect of cerium oxide nanoparticles on asparagus lettuce cultured in an agar medium. Environ. Sci.: Nano, 2014, 1 (5), 459 - 465. DOI: 10.1039/C4EN00025K

55. An FP, et al. (Daya Bay Collaboration). Spectral measurement of electron antineutrino oscillation amplitude and frequency at Daya Bay. Phys Rev Lett, 2014, 112: 061801

56. Wang B, He X, Zhang ZY*, Feng WY*, Zhao YL. Metabolism of nanomaterials in vivo: circulation and organ clearance. Acc Chem Res, 2013, 46(3): 761-769 DOI: 10.1021/ar2003336

57. He X, Ma YH, Zhang P, Li YY, Zhang ZY*. Quantifying and imaging engineered nanomaterials in vivo: challenges and techniques. Small, 2013, 9(9-10): 1482-1491, 10.1002/smll.201201502

58. Feng QZ, Zhang ZY*, Chen Y, Liu LY, Zhang ZJ, Chen CZ. Adsorption and Desorption Characteristics of Arsenic on Soils: Kinetics, Equilibrium, and Effect of Fe(OH)3 Colloid, H2SiO3 Colloid and Phosphate. Procedia Environmental Sciences, 2013, 18: 26-36

59. Zhang XY, He X, Li YY, Zhang ZY*, Ma YH, Li FM, Liu JM*. A cytotoxicity study of fluorescent carbon nanodots using human bronchial epithelial cells. J Nanosci Nanotechnol. 2013, 13(8): 5254-5259

60. Xue LX, He X, Li YY, Qu MH*, Zhang ZY*. Pulmonary toxicity of ceria nanoparticles in mice after intratracheal instillation. J Nanosci Nanotechnol, 2013, 13: 6575-6580 

61. An FP, et al. (Daya Bay Collaboration). Improved measurement of electron antineutrino disappearance at Daya Bay. Chinese Phys. C, 37, 011001 (2013) DOI: 10.1088/1674-1137/37/1/011001

62. Zhang P, Ma YH, Zhang ZY*, He X, Zhang J, Guo Z, Tai RZ, Zhao YL, Chai ZF. Biotransformation of ceria nanoparticles in cucumber plants. ACS Nano, 2012, 6(11): 9943-9950 DOI: 10.1021/nn303543n

63. Zhang P, He X, Ma YH, Lu K, Zhao YL, Zhang ZY*. Distribution and bioavailability of ceria nanoparticles in an aquatic ecosystem model. Chemosphere, 2012, 89: 530-535  DOI: 10.1016/j.chemosphere.2012.05.044

64. He X#, Kuang YS#, Li YY, Zhang HF, Ma YH, Bai W, Zhang ZY*, Wu ZQ*, Zhao YL, Chai ZF. Changing exposure media can reverse the cytotoxicity of ceria nanoparticles for Escherichia coli. Nanotoxicology, 2012, 6:233-40. DOI:10.3109/17435390.2011.569097

65. Zhang P#, Ma YH#, Zhang ZY*, He X, Guo Z, Tai RZ, Ding YY, Zhao YL, Chai ZF. Comparative toxicity of nanoparticulate/bulk Yb2O3 and YbCl3 to cucumber (Cucumis sativus). Environ Sci Technol, 2012, 46(3): 1834-1841

66. Cui JA, Zhang ZY*, Bai W, Zhang LG, He X, Ma YH, Liu Y, Chai ZF. Effects of rare earth elements La and Yb on the morphological and functional development of zebrafish embryos. J Environ Sci, 2012, 24(2): 209-213 DOI: 10.1016/S1001-0742(11)60755-9

67. Feng QZ, Zhang ZY*, Ma YH, He X, Zhao YL, Chai ZF. Adsorption and desorption characteristics of arsenic onto ceria nanoparticles. Nanoscale Res Lett, 2012, 7:84

68. Lin DH, Tian XL, Li TT, Zhang ZY, He X, Xing BS. Surface-bound humic acid increased Pb2+ sorption on carbon nanotubes. Environ Pollut, 2012, 167: 138-147 doi:10.1016/j.envpol.2012.03.044

69. An FP, et al. (Daya Bay Collaboration). Observation of electron-antineutrino disappearance at Daya Bay. Phys Rev Lett, 2012, 108: 171803

70. An FP, et al. (Daya Bay Collaboration). A side-by-side comparison of Daya Bay antineutrino detectors. Nucl Instrum Meth A, 2012, 685: 78-97

71. He X, Zhang ZY*, Liu JS, Ma YH, Zhang P, Li YY, Wu ZQ, Zhao YL*, Chai ZF. Quantifying the biodistribution of nanoparticles. Nat Nanotech, 2011, 6(12): 755

72. Zhang HF He X, Zhang ZY*, Zhang P, Li YY, MaYH, KuangYS, ZhaoYL, Chai ZF. Nano-CeO2 exhibits adverse effects at environmental relevant concentrations. Environ Sci Technol, 2011, 45(8): 3725-3730

73. Li ZJ, Zhang ZY*, Yu M, Zhou YL, Zhao YL. Effects of lanthanum on calcium and magnesium contents and cytoplasmic streaming of internodal cells of Chara corallina. Biol Trace Elem Res, 2011, 143(1): 555-61

74. Kuang YS, He X, Zhang ZY*, Li YY, Zhang HF, Ma YH, Wu ZQ*, Zhao YL, Chai ZF. Comparison study on the antibacterial activity of nano- or bulk- cerium oxide. J. NanoSci. Nanotechnol., 2011, 11(5): 4103-4108

75. Feng QZ, Li HF, Zhang ZY, Lin JM. Chemiluminescence accompanied by the reaction of gold nanoparticles with luminal, Analyst, 2011, 136(10):2156-60

76. Wan L, Nie GJ, Zhang J, Luo YF, Zhang P, Zhang ZY, Zhao BL. β-amyloid peptide increases levels of iron content and oxidative stress in human cell and C. elegans models of Alzheimer’s disease. Free Radic Biol Med., 2011, 50 (1): 122-129

77. Ma YH, He X, Zhang P, Zhang ZY*, Guo Z, Tai RZ, Xu ZJ, Zhang LJ, Ding YY, Zhao YL, Chai ZF. Phytotoxicity and biotransformation of La2O3 nanoparticles in a terrestrial plant cucumber (Cucumis sativus). Nanotoxicology, 2011, 5: 743-753. DOI: 10.3109/17435390. 2010.545487

78. Zhang ZY*, Zhao YL, Chai ZF. Nuclear analytical techniques for nanotoxicology studies. Proc. Radiochim. Acta 2011, 1, 345–348 DOI 10.1524/rcpr.2011.0061

79. Zhang ZY*, He X, Zhang HF, Ma YH, Zhang P, Ding YY, and Zhao YL. Uptake and distribution of ceria nanoparticles in cucumber plants. Metallomics, 2011, 3 (8): 816-822

80. Ding YY, Zhang ZY. Preparation of Gd loaded liquid scintillator for Daya Bay neutrino experiment. AIP Conference Proceedings, 2010, CP1235: 294-300

81. Bai W, Zhang ZY*, Tian WJ, Zhao YL, Chai ZF, Liu NQ. Developmental toxicity of zinc oxide nanoparticles to zebrafish embryo: a physicochemical study of toxicity mechanism. J Nanopart Res, 2010, 12: 1645-1654

82. Bai W, Tian WJ, Zhang ZY*, He X, Ma YH, Liu NQ, Chai ZF. Effects of copper nanoparticles on the development of zebrafish embryos. J. Nanosci. Nanotechnol., 2010, 10 (12): 8670-8676

83. Lu K, Zhang ZY*, He X, Ma YH, Zhou KB, Zhang HF, Bai W, Ding YY, Wu ZQ*, Zhao YL, Chai ZF. Bioavailability and distribution and of ceria nanoparticles in simulated aquatic ecosystems, quantification with a radiotracer technique. J Nanosci Nanotechnol, 2010, 10 (12): 8658-8662

84. Ma YH, Kuang LL, He X, Bai W, Ding YY, Zhang ZY*, Zhao YL, Chai ZF. Effects of rare earth oxide nanoparticles on root elongation of plants. Chemosphere, 78 (2010) 273–279

85. He X, Zhang HF, Ma YH, Bai W, Zhang ZY*, Lu K, Ding YY, Zhao YL, Chai ZF. Lung deposition and extrapulmonary translocation of nano-ceria after intratracheal instillation. Nanotechnology, 2010, 21: 285103

86. Tian X, Zhou S, Zhang Z, He X, Yu M, Lin D. Metal impurities dominate the sorption of a commercially available carbon nanotube for Pb(II) from water. Environ Sci Technol, 2010, 44(21): 8144-8149

87. Zhang HF, He X, Bai W, Guo XM, Zhang ZY*, Chai ZF, Zhao YL. Ecotoxicological assessment of lanthanum with Caenorhabditis elegans in liquid medium. Metallomics, 2010, 2 (12): 806 – 810

88. Liu XS, Zhang H, Zhang ZY, Li XE, Han XW, Wu YP. Content of rare earth elements in Salvia miltiorrhiza bunge from different areas. J Rare Earths, 2010, 28(Suppl1): 510-512

89. Yin XY, He M, Dong KJ, Wu SY, Zhang JS, Zhang JL, Wang TX, Cui AnZ, Ouyang YG, Zhang ZY, Yuan J, Jiang S. Measurement of 151Sm with the HI-13 accelerator mass spectrometry system. Nucl. Instrum. Meth. B, 2010, 268(10): 1689-1691.

90. Zhang ZY*, Zhao YL, Chai ZF. Applications of radiotracer techniques for the pharmacology and toxicology studies of nanomaterials. Chin Sci Bull, 2009, 54: 173-182

91. Wang ZM, Yang CG, Guan MY, Zhong WL, Liu JC, Zhang ZY, Ding YY, Wang RG, Cao J, Wang YF, Lu HQ. Study of a prototype detector for the Daya Bay neutrino experiment. Nucl Instrum Meth A. 2009, 602: 489-493

92. Lu ZB, Nie GJ, Li YY, Shan SL, Tao Y, Cao YL, Zhang ZY, Liu NQ, Ponka P, Zhao BL. Overexpression of Mitochondrial Ferritin Sensitizes Cells to Oxidative Stress Via an Iron-Mediated Mechanism. Antioxid Redox Signal. 2009, 11(8): 1791-1803

93. Ding Y, Gundorin NA, Zhang Z, Nemchenok IB, Pikelner LB. A liquid scintillator for thermal neutrons detection. Functional Materials, 2009, 16(1): 73-75 

94. Ding YY, Zhang ZY*, Liu JC, Wang ZM, Zhou PJ, Zhao YL. A new gadolinium-loaded liquid scintillator for reactor neutrino detection. Nucl Instrum Meth A, 2008, 584, 238-243

95. Li ZJ, Zhang ZY*, Jiang WJ, Yu M, Zhou YL, Zhao YL, Chai ZF. Direct measurement of lanthanum uptake and distribution in internodal cells of Chara. Plant Sci, 2008, 174 (5): 496-501

96. He X, Zhang ZY*, Zhang HF, Zhao YL, Chai ZF. Neurotoxicological evaluation of long-term lanthanum chloride exposure in rats. Toxicol Sci, 2008, 103(2): 354-61

97. He R, Wang XX, Fang K, Liu NQ, Zhang ZY, Huang YY, He W, Lei H. Elemental distributions in rat olfactory bulbs after exposure to MnCl2 measured by synchrotron radiation X-ray fluorescence. J Radioanal Nucl Chem, 2007, 272 (3), 589-593.

98. Li ZJ, Zhang ZY*, Wang Y, Li FL, Chai ZF. Uptake and elimination of lanthanum by excised roots of Triticum aestivum L., J Radioanal Nucl Chem, 2007, 272: 523-525

99. He X, Zhang ZY*, Feng LX, Li ZJ, Yang JH, Zhao YL, Chai ZF. Effects of acute lanthanum exposure on calcium absorption in rats, J Radioanal Nucl Chem, 2007, 272: 557-559

100. Feng L X, Xiao H Q, He X, Li Z J, Li F L, Liu N Q, Chai Z F, Zhao Y L, Huang Y Y, He W, Zhang Z Y *. Element distribution in the brain of rats exposed to lanthanum measured by synchrotron radiation X-ray fluorescence, J Radioanal Nucl Chem, 2007, 272: 333-337

101. Wei CY, Zhang ZY. Multivariate analysis of elements in Chinese brake fern as determined using neutron activation analysis, Biol Trace Elem Res, 2007, 115: 277-290

102. Feng LX, He X, Xiao HQ, Li ZJ, Li FL, Liu NQ, Chai ZF, Zhao YL, Zhang ZY*. Ytterbium and trace element distribution in brain and organic tissues of offspring rats after prenatal and postnatal exposure to ytterbium, Biol Trace Elem Res, 2007, 117: 89-104

103. He X, Feng LX, Xiao HQ, Li ZJ, Liu NQ, Zhao YL, Zhang ZY*, Chai ZF*, Huang YY. Unambiguous effects of lanthanum? Toxicol Lett, 2007, 170: 94-96

104. Ding YY, Zhang ZY*, Zhou PJ, Liu JC, Zhao YL. Research and development of gadolinium loaded liquid scintillator for Daya Bay neutrino experiment. J Rare Earth, 2007, 25 (Spec Issue): 310-313

105. Zhiyong Zhang and Zhifang Chai. Neutron activation analysis in China: present status and future perspectives. 放射化分析(日). 2007, No. 27, 4-22

106. Feng LX, Xiao HQ, He X, Li ZJ, Li FL, Liu NQ, Chai ZF, Zhao YL, Zhang ZY*. Long-term effects of Lanthanum intake on the neurobehavioral development of the rat. Neurotoxicol. Teratol. 2006, 28: 119-124

107. Zhang Zhiyong, Chen Chunying, Feng Weiyue, Chai Zhifang. Isotopic tracer studies on the metabolism and functional roles of mineral elements in institute of high energy physics, China. J. Nucl. Sci. Tech. 2006, 43(4): 450-454

108. Feng LX, Xiao HQ, He X, Li ZJ, Li FL, Liu NQ, Zhao YL, Huang YY, Zhang ZY*, Chai ZF*. Neurotoxicological Consequence of Long-term Exposure to Lanthanum, Toxicol. Lett. 2006, 165: 112-120

109. Z. Y. Zhang, N. Q. Liu*, F. L. Li, J. Zhang, H. Zhu, C. Qin, Z. Y. Zou, X. W. Tang. Characterization of Fe, Cu, and Zn in organs of PDAPP transgenic mice by XRF. X-Ray Spectrometry, 2006, 35: 253-256

110. Nianqing Liu, Aijun Zuo, Dongchun Liang, Zhiyong Zhang, Gang Guo, Zhifang Chai. Effect of Iodine Supplement on Iodine Status and 5'-Deiodinase Activity in the Brain of Neonatal Rats with Iodine Deficiency. Biol Trace Elem Res, 2006, 114: 207-216

111. Xuxia Wang, Junchao Qian, Rui He, Li Wei, Nianqing Liu, Zhiyong Zhang, Yuying Huang, Hao Lei. Delayed Changes in T1-Weighted Signal Intensity in A Rat Model of 15-Minute Transient Focal Ischemia Studied by Magnetic Resonance Imaging/Spectroscopy and Synchrotron Radiation X-Ray Fluorescence. Magnetic Resonance in Medicine, 2006, 56: 474-480

112. Xiao HQ, Li FL, Zhang ZY, Feng LX, Li ZJ, Yang JH, Chai ZF*. Distribution of Ytterbium-169 in Rat after Intravenous Injection. Toxicol. Lett. 2005, 155, 247-252

113. Xiao HQ, Zhang ZY, Li FL, Feng LX, Li ZJ, Yang JH, Chai ZF*. Accumulation and Distribution of Samarium-153 in Rat Brain After Intraperitoneal Injection. Biol. Trace Elem Res. 2005, 104(1):33-40

114. Feng LX, Xiao HQ, He X, Zhang ZY*, Liu NQ, Zhao YL, Huang YY. Spatial distribution of elements in the brain of rats measured by synchrotron radiation X-ray fluorescence. High Energy Physics and Nuclear Physics, 2005, 29 (10): 1012-1016

115. Z. F. Chai, Z. Y. Zhang, W. Y. Feng, C. Y. Chen, D. D. Xu, X. L. Hou. Study of chemical speciation of trace elements by molecular activation analysis and other nuclear techniques. J Anal Atom Spectr, 2004, 19: 26-33

116. Z. Y. Zhang, F. L. Li, L. Xu, N. Liu, H. Q. Xiao, Z. F. Chai. Study of binding properties of lanthanum to wheat roots by NAA. J Radioanal Nucl Chem, 2004, 259 (1): 47-49.

117. Diandou Xu, Weike Zhong, Linlin Deng, Zhifang Chai, Xueying Mao, Zhiyong Zhang. Determination of extractable organic halogens in pine needles by neutron activation analysis. J Radioanal Nucl Chem, 2004, 259 (1): 129-134

118. N. Q. Liu, F. Zhang, X. F. Wang, Z. Y. Zhang, Z. F. Chai, Y. Y. Huang, W. He, X. Q. Zhao, A. J. Zuo and R. Yang. Element distribution in the brain sections of rats measured by synchrotron radiation X-ray fluorescence, Spectrochimica Acta Part B: Atomic Spectroscopy, 2004, 59 (2): 255-260

119. Zhang Z. Y.  and Chai Z. F.. Isotopic tracer studies of chemical behavior of rare earth elements in environmental and biological sciences. Radiochimica Acta, 2004, 92: 355-358

120. Z. Y. Zhang, J. H. Yang, H. Ouyang, Z. J. Li, Z. F. Chai, et al. Study of trace impurities in heroin by neutron activation analysis. J Radioanal Nucl Chem, 2004, 262 (1): 295-297

121. Zhang Z Y*, Wang Y Q, Li F L, Xiao H Q and C F Chai. Distribution characteristics of rare earth elements in plants from a rare earth ore area. J Radioanal Nucl Chem, 2002, 252: 461-465

122. F L Li, Y Q Wang, Z Y Zhang, J X Sun, H Q Xiao and C F Chai. Distribution of samarium and ytterbium in rats measured by enriched stable isotope tracer technique and INAA. J Radioanal Nucl Chem, 2002, 251: 437-441

123. Zhifang Chai, Xueying Mao, Zhaohui Hu, Zhiyong Zhang, Chunying Chen, Weiyu Feng, Sumin Hu, Hong Ouyang. Overview of the methodology of nuclear analytical techniques for speciation studies of trace elements in the biological and environmental sciences. Anal Bioanal Chem, 2002, 372: 407-411

124. Z Y Zhang, Y Q Wang, F L Li and C F Chai, Determination of REEs in chloroplasts of Brassia napus by INAA and biochemical separation techniques, J Radioanal Nucl Chem 2001, 247(3): 557~560

125. Zhang Zhiyong, Wang Xiangyun*, Wu Yonghui, Liu Yuanfang, Preparation of 186, 188Re with High Specific Activity by the Szilard-Chalmers Reaction. J. Label. Compds. Radiopharm. 2000, 43 (1): 55-64

126. ZHANG Zhiyong, WANG Yuqi, SUN Jingxin, LI Fuliang, CHAI Zhifang, XU Lei, Li Xin, Cao Guoyin. Determination of rare earth elements in plant protoplasts by MAA. Chinese Science Bulletin, 2000, 45 (16): 1497-1499

127. Y. Q. Wang, J. X. Sun, F. Q. Guo, Z. Y. Zhang, H. M. Chen, L. Xu, G. Y. Cao, Study on Binding of REEs with Water-Soluble Polysaccharides in Fern, Biol Trace Elem Res, 1999, 71-72: 103-108

128. Wang Y-Q, Jiang P, Guo F-Q, Zhang Z-Y, Sun J-X, Xu L, Cao G-Y, REE bound DNA in natural plant, Science in China (B), 1999,42 (4): 357~362

129. Zhu Zhihong, Wu Yonghui, Zhang Zhiyong, Liu Yuanfang. Direct Labeling of Antibodies IgG with 186Re Using Sodium Glucoheptonate. Radiochim Acta, 1997, 79: 105-108

已指导学生

姜文君  硕士研究生  070301-无机化学  

张海凤  博士研究生  070322-生物无机化学  

丁雅韵  博士研究生  070322-生物无机化学  

张鹏  博士研究生  070322-生物无机化学  

李媛媛  博士研究生  070301-无机化学  

张珺哲  博士研究生  070301-无机化学  

王国华  博士研究生  070301-无机化学  

谢昌健  博士研究生  070301-无机化学  

现指导学生

罗文赫  博士研究生  070301-无机化学  

焦春磊  博士研究生  070301-无机化学  

戴婉琴  硕士研究生  070301-无机化学  

孙明辉  博士研究生  070301-无机化学  

宋翥达  硕士研究生  070301-无机化学