基本信息
刘欣 女 博导 中国科学院北京基因组研究所(国家生物信息中心)
email: liuxin@big.ac.cn
address: 北京市朝阳区北辰西路1号院104号楼
postalCode: 100101
email: liuxin@big.ac.cn
address: 北京市朝阳区北辰西路1号院104号楼
postalCode: 100101
招生信息
招生专业
071007-遗传学
招生方向
复杂疾病的遗传流行病学研究
教育背景
1997-09--2002-02 美国约翰霍普金斯大学 博士学位1988-09--1993-07 山东医科大学 学士学位
工作经历
工作简历
2015-01~现在, 中国科学院北京基因组研究所, 研究员2007-01~2015-01,美国西北大学, 助理教授2004-02~2006-12,美国加州大学旧金山分校, 博士后2002-02~2003-12,美国约翰霍普金斯大学布隆博格公共卫生学院, 博士后1997-09~2002-02,美国约翰霍普金斯大学, 博士学位1988-09~1993-07,山东医科大学, 学士学位
教授课程
精准医疗基础与临床遗传流行病学生物统计学
出版信息
发表论文
(1) Clinical and Genetic Characterization of EBV-associated T/NK lymphoproliferativediseases, Journal of Allergy and Clinical Immunology, 2022, 第 10 作者(2) NBAS, a gene involved in cytotoxic degranulation, is recurrently mutated in pediatric hemophagocytic lymphohistiocytosis, JOURNAL OF HEMATOLOGY & ONCOLOGY, 2022, 通讯作者(3) Germline variants in UNC13D and AP3B1 are enriched in COVID-19 patients experiencing severe cytokine storms, EUROPEAN JOURNAL OF HUMAN GENETICS, 2021, 第 9 作者(4) Ecological principle meets cancer treatment: treating children with acute myeloid leukemia with low-dose chemotherapy, NATIONAL SCIENCE REVIEW, 2019, 第 13 作者(5) Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia, CELL RESEARCH, 2018, 第 38 作者(6) Genome-wide association study of maternal genetic effects and parent-of-origin effects on food allergy, MEDICINE, 2018, 通讯作者(7) PDGFRB mutation and tyrosine kinase inhibitor resistance in Ph-like acute lymphoblastic leukemia, BLOOD, 2018, 通讯作者(8) Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth, NATURE COMMUNICATIONS, 2017, 第 8 作者(9) Epigenome-wide association study links site-specific DNA methylation changes with cow's milk allergy, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2016, 第 9 作者(10) Racial Disparity in the Associations of Cotinine with Insulin Secretion: Data from the National Health and Nutrition Examination Survey, 2007-2012, PLOS ONE, 2016, 第 5 作者(11) Blood methylomics in response to arsenic exposure in a low-exposed US population, JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, 2014, 第 1 作者(12) Maternal preconception body mass index and offspring cord blood DNA methylation: Exploration of early life origins of disease, ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2014, 通讯作者(13) Microsomal epoxide hydrolase (EPHX1) polymorphisms are associated with aberrant promoter methylation of ERCC3 and hematotoxicity in benzene-exposed workers, ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2013, 第 9 作者(14) Longitudinal trajectory of vitamin D status from birth to early childhood in the development of food sensitization, PEDIATRIC RESEARCH, 2013, 通讯作者(15) Individual variation and longitudinal pattern of genome-wide DNA methylation from birth to the first two years of life, EPIGENETICS, 2012, 第 2 作者(16) Associations between gene polymorphisms in fatty acid metabolism pathway and preterm delivery in a US urban black population, HUMAN GENETICS, 2012, 通讯作者(17) Gene-Vitamin D Interactions on Food Sensitization: A prospective birth cohort study, ALLERGY, 2011, (18) Fine-Mapping of Prostate Cancer Aggressiveness Loci on Chromosome 7q22-35, PROSTATE, 2011, 第 1 作者(19) Association between short sleep duration and the risk of sensitization to food and aero allergens in rural Chinese adolescents, CLINICAL AND EXPERIMENTAL ALLERGY, 2011,
科研活动
科研项目
( 1 ) ****启动, 负责人, 研究所自主部署, 2015-01--2017-12( 2 ) 中国科学院“**择优”, 负责人, 中国科学院计划, 2016-01--2018-12( 3 ) 儿童噬血细胞综合征的遗传突变研究, 负责人, 国家任务, 2016-01--2019-12( 4 ) 职业人群队列建立及精准医学研究, 负责人, 中国科学院计划, 2015-09--2018-12( 5 ) 慢性活动性EB病毒感染的遗传变异研究, 负责人, 国家任务, 2019-01--2022-12( 6 ) 白血病形成及其在药物作用下的细胞异质性演化, 参与, 国家任务, 2019-01--2023-12( 7 ) 靶点基因在难治复发AML中的演化及新靶点的发现, 负责人, 国家任务, 2021-12--2024-11