基本信息
朱本占  男  博导  中国科学院生态环境研究中心
电子邮件: bzhu@rcees.ac.cn
通信地址: 北京市海淀区双清路18号环境科学楼613室
邮政编码: 100085

研究领域

自由基和过渡金属离子的化学与毒理学协同毒性作用机理


招生信息

   
招生专业
083001-环境科学
招生方向
环境科学,毒理学

教育背景

1994-01--1999-06   以色列希伯来大学哈达萨医学院   哲学博士研究生
1986-09--1989-07   中科院兰州化物所   理学硕士研究生
1981-09--1983-07   山东济宁师专   大学专科

教授课程

自由基化学生物学
化学系列讲座
环境与健康研究进展
自由基生物学导论

专利与奖励

   
奖励信息
(1) 中国科学院杰出科技成就奖, 部委级, 2013
专利成果
[1] 朱本占, 巢细娟. 一种促进Ru(II)金属络合物细胞核摄取的方法. CN: CN105039242A, 2015-11-11.

[2] 朱本占, 毛莉. 检测卤代芳烃类有机物的方法. CN: CN102809559A, 2012-12-05.

出版信息

   
发表论文
[1] Li, PeiLin, Huang, ChunHua, Mao, Li, Li, Jun, Sheng, ZhiGuo, Zhu, BenZhan. An unprecedented free radical mechanism for the formation of DNA adducts by the carcinogenic N-sulfonated metabolite of aristolochic acids. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2023, 205: 332-345, http://dx.doi.org/10.1016/j.freeradbiomed.2023.05.005.
[2] Wang, Anna, Zhu, BenZhan, Huang, ChunHua, Zhang, WeiXian, Wang, Mengye, Li, Xuchun, Ling, Li, Ma, Jun, Fang, Jingyun. Generation mechanism of singlet oxygen from the interaction of peroxymonosulfate and chloride in aqueous systems. WATER RESEARCH[J]. 2023, 235: http://dx.doi.org/10.1016/j.watres.2023.119904.
[3] Chen Shen, ZhiGuo Sheng, Jie Shao, Miao Tang, Li Mao, ChunHua Huang, ZhiHui Zhang, BenZhan Zhu. Mechanistic investigation of the differential synergistic neurotoxicity between pesticide metam sodium and copper or zinc. CHEMOSPHERE[J]. 2023, 328: http://dx.doi.org/10.1016/j.chemosphere.2023.138430.
[4] Qin, Li, Huang, ChunHua, Liu, CuiQing, Zhao, ChuanFang, Li, Pei Lin, Tang, TianShu, Li, Jun, Xie, LinNa, Shao, Bo, Shao, Jie, Mao, Li, Li, Ran, Zhang, Lu, Zhu, BenZhan. Molecular mechanism for the activation of the potent hepatotoxin acetylhydrazine: Identification of the initial N-centered radical and the secondary C-centered radical intermediates. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2023, 204: 20-27, http://dx.doi.org/10.1016/j.freeradbiomed.2023.04.010.
[5] Quan, Zhuo, Mao, Li, Tang, YiQi, Lei, Ming, Zhu, BenZhan, Liu, YaJun. Mechanistic Investigation of H2O2-dependent Chemiluminescence from Tetrabromo-1,4-Benzoquinone. CHEMPHYSCHEM[J]. 2022, 23(5): http://dx.doi.org/10.1002/cphc.202100885.
[6] Dong, Junjie, Huang, Chunhua, Guo, Shaoshi, Xia, Ye, Hou, Yue, Yang, Chunfan, Zhang, Xianwang, Jie, Jialong, Zhu, BenZhan, Su, Hongmei. Free-Radical-Mediated Photoinduced Electron Transfer between 6-Thioguanine and Tryptophan Leading to DNA-Protein-Like Cross-Link. JOURNAL OF PHYSICAL CHEMISTRY B[J]. 2022, 126(1): 14-22, http://dx.doi.org/10.1021/acs.jpcb.1c03380.
[7] 朱本占, 张静, 唐苗, 黄春华, 邵杰. 致癌性卤代醌类消毒副产物造成 DNA 损伤的分子机理研究. 化学进展[J]. 2022, 34(1): 227-236, http://lib.cqvip.com/Qikan/Article/Detail?id=7106740073.
[8] Zhu, BenZhan, Tang, Miao, Huang, ChunHua, Mao, Li. Detecting and Quantifying Polyhaloaromatic Environmental Pollutants by Chemiluminescence-Based Analytical Method. MOLECULES[J]. 2021, 26(11): http://dx.doi.org/10.3390/molecules26113365.
[9] Tang, YiQi, Mao, Li, Zhu, BenZhan, Liu, YaJun. Mechanistic Study on Chemiluminescence of Chloranilic Acid by Co(II)-Mediated Fenton-like System. JOURNAL OF ORGANIC CHEMISTRY[J]. 2021, 86(6): 4472-4482, http://dx.doi.org/10.1021/acs.joc.0c02915.
[10] Shao, Jie, Yan, ZhuYing, Tang, Miao, Huang, ChunHua, Sheng, ZhiGuo, Chen, Jing, Shao, Bo, Zhu, BenZhan. Potent oxidation of DNA by Ru(ii) tri(polypyridyl) complexes under visible light irradiation via a singlet oxygen-mediated mechanism. INORGANIC CHEMISTRY FRONTIERS[J]. 2021, 8(14): 3421-+, http://dx.doi.org/10.1039/d0qi01518k.
[11] Yan, ZhuYing, Chen, Jing, Shao, Jie, Jiao, ZeQing, Tang, TianShu, Tang, Miao, Sheng, ZhiGuo, Mao, Li, Huang, Rong, Huang, ChunHua, Zhang, ZhiHui, Su, HongMei, Zhu, BenZhan. The cell-impermeable Ru(II) polypyridyl complex as a potent intracellular photosensitizer under visible light irradiation via ion-pairing with suitable lipophilic counter-anions. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2021, 171: 69-79, http://dx.doi.org/10.1016/j.freeradbiomed.2021.04.035.
[12] Xie, LinNa, Huang, ChunHua, Xu, Dan, Qin, Li, Li, Feng, Shan, GuoQiang, Liu, ZhiSheng, Cao, Dong, Geng, FangLan, Mao, Li, Shao, Jie, Sheng, ZhiGuo, Zhu, BenZhan. Structure-Activity Relationship Investigation on Reaction Mechanism between Chlorinated Quinoid Carcinogens and Clinically-Used Aldoxime Nerve-Agent Antidote under Physiological Condition. CHEMICAL RESEARCH IN TOXICOLOGY[J]. 2021, 34(4): 1091-1100, http://dx.doi.org/10.1021/acs.chemrestox.0c00504.
[13] Shao, Bo, Mao, Li, Tang, Miao, Yan, ZhuYing, Shao, Jie, Huang, ChunHua, Sheng, ZhiGuo, Zhu, BenZhan. Caffeic Acid Phenyl Ester (CAPE) Protects against Iron-Mediated Cellular DNA Damage through Its Strong Iron-Binding Ability and High Lipophilicity. ANTIOXIDANTS[J]. 2021, 10(5): http://dx.doi.org/10.3390/antiox10050798.
[14] Mao, Li, Huang, ChunHua, Shao, Bo, Qin, Li, Tang, Miao, Yan, ZhuYing, Liu, ZhiSheng, Shao, Jie, Sheng, ZhiGuo, Zhu, BenZhan. The critical role of superoxide anion radicals on delaying tetrachlorohydroquinone autooxidation by penicillamine. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2021, 163: 369-378, http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.014.
[15] Zhu, BenZhan, Tang, Miao, Huang, ChunHua, Mao, Li, Shao, Jie. Mechanistic Study on Oxidative DNA Damage and Modifications by Haloquinoid Carcinogenic Intermediates and Disinfection Byproducts. CHEMICAL RESEARCH IN TOXICOLOGY[J]. 2021, 34(7): 1701-1712, http://dx.doi.org/10.1021/acs.chemrestox.1c00158.
[16] Gao, HuiYing, Huang, ChunHua, Mao, Li, Shao, Bo, Shao, Jie, Yan, ZhuYing, Tang, Miao, Zhu, BenZhan. First Direct and Unequivocal Electron Spin Resonance Spin-Trapping Evidence for pH-Dependent Production of Hydroxyl Radicals from Sulfate Radicals. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2020, 54(21): 14046-14056, http://dx.doi.org/10.1021/acs.est.0c04410.
[17] Shao, Jie, Huang, Chun-hua, Ben-Zhan Zhu. Potent Oxidation of DNA by Haloquinoid Disinfection Byproducts to the More Mutagenic Imidazolone dIz via an Unprecedented Haloquinone-Enoxy Radical-Mediated Mechanism. Environmental Science & Technology[J]. 2020, 54: 6244-6253, [18] Zhu, BenZhan, Xu, Dan, Qin, Li, Huang, ChunHua, Xie, LinNa, Mao, Li, Shao, Jie, Kalyanaraman, Balaraman. An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2020, 146: 150-159, http://dx.doi.org/10.1016/j.freeradbiomed.2019.07.009.
[19] Huang, ChunHua, Xu, Dan, Qin, Li, Li, PeiLin, Tang, TianShu, Zhu, BenZhan. Unusual Two-Step Claisen-type Rearrangement Reaction under Physiological Conditions. JOURNAL OF ORGANIC CHEMISTRY[J]. 2020, 85(23): 14945-14953, https://www.webofscience.com/wos/woscc/full-record/WOS:000598137400012.
[20] Ren, Liting, Feng, Wenya, Shao, Jie, Ma, Juan, Xu, Ming, Zhu, BenZhan, Zheng, Nanfeng, Liu, Sijin. Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting. THERANOSTICS[J]. 2020, 10(14): 6384-6398, http://dx.doi.org/10.7150/thno.45558.
[21] Huang, Rong, Feng, FengPing, Huang, ChunHua, Mao, Li, Tang, Miao, Yan, ZhuYing, Shao, Bo, Qin, Li, Xu, Tao, Xue, YanHong, Zhu, BenZhan. Chiral Os(II) Polypyridyl Complexes as Enantioselective Nuclear DNA Imaging Agents Especially Suitable for Correlative High-Resolution Light and Electron Microscopy Studies. ACS APPLIED MATERIALS & INTERFACES[J]. 2020, 12(3): 3465-3473, https://www.webofscience.com/wos/woscc/full-record/WOS:000509428300016.
[22] Mao, Li, Huang, ChunHua, Shao, Jie, Qin, Li, Xu, Dan, Shao, Bo, Zhu, BenZhan. An unexpected antioxidant and redox activity for the classic copper-chelating drug penicillamine. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2020, 147: 150-158, http://dx.doi.org/10.1016/j.freeradbiomed.2019.12.013.
[23] Shao, Jie, Huang, ChunHua, Shao, Bo, Qin, Li, Xu, Dan, Li, Feng, Qu, Na, Xie, LinNa, Kalyanaraman, Balaraman, Zhu, BenZhan. Potent Oxidation of DNA by Haloquinoid Disinfection Byproducts to the More Mutagenic Imidazolone dlz via an Unprecedented Haloquinone-Enoxy Radical-Mediated Mechanism. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2020, 54(10): 6244-6253, https://www.webofscience.com/wos/woscc/full-record/WOS:000537151000035.
[24] Mao, Li, Gao, HuiYing, Huang, ChunHua, Qin, Li, Huang, Rong, Shao, Bo, Shao, Jie, Zhu, BenZhan. Unprecedented strong intrinsic chemiluminescence generation from degradation of halogenated hydroxy-quinoid pollutants by Co(II)-mediated advanced oxidation processes: The critical role of site -specific production of hydroxyl radicals. CHEMICAL ENGINEERING JOURNAL[J]. 2020, 394: http://dx.doi.org/10.1016/j.cej.2020.125023.
[25] Ben-Zhan Zhu. First Unequivocal Identification of the Critical C-centered Acyl Radicals from the Anti-Tuberculosis Drug Isoniazid and its Close Hydrazide Analogs by Complementary Applications of ESR Spin-trapping and HPLC/MS Methods. Free Radic. Biol. Med.. 2020, [26] Qin, Li, Huang, ChunHua, Mao, Li, Shao, Bo, Zhu, BenZhan. First unequivocal identification of the critical acyl radicals from the anti- tuberculosis drug isoniazid and its hydrazide analogs by complementary applications of ESR spin-trapping and HPLC/MS methods. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2020, 154: 1-8, http://dx.doi.org/10.1016/j.freeradbiomed.2020.04.021.
[27] Dan Xu, ChunHua Huang, Li Qin, LinNa Xie, Li Mao, Jie Shao, Balaraman Kalyanaraman, BenZhan Zhu. Corrigendum to "An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids" Free Radic. Biol. Med. 146 (2020) 150–159/FRBM_2019_405. FREE RADICAL BIOLOGY AND MEDICINE. 2020, 152: 869-869, http://dx.doi.org/10.1016/j.freeradbiomed.2020.03.028.
[28] Mao, Li, Gao, HuiYing, Shao, Bo, Huang, ChunHua, Zhu, BenZhan. Molecular mechanisms and potential applications of the intrinsic chemiluminescence produced from the degradation of haloaromatic pollutants during environmentally-friendly advanced oxidation processes. ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY[J]. 2020, 6(9): 2259-2274, http://dx.doi.org/10.1039/d0ew00325e.
[29] Xu, Dan, Huang, ChunHua, Qin, Li, Xie, LinNa, Mao, Li, Shao, Jie, Kalyanaraman, Balaraman, Zhu, BenZhan. An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids (vol 146, pg 150, 2020). FREE RADICAL BIOLOGY AND MEDICINEnull. 2020, 152: 869-869, https://www.webofscience.com/wos/woscc/full-record/WOS:000546582900012.
[30] Huang, ChunHua, Xu, Dan, Qin, Li, Tang, TianShu, Shan, GuoQiang, Xie, LinNa, Li, PeiLin, Mao, Li, Shao, Jie, Zhu, BenZhan. Unexpected activation of N-alkyl hydroxamic acids to produce reactive N-centered free radicals and DNA damage by carcinogenic chlorinated quinones under normal physiological conditions. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2020, 146: 70-78, http://dx.doi.org/10.1016/j.freeradbiomed.2019.10.009.
[31] Shao, Bo, Mao, Li, Shao, Jie, Huang, ChunHua, Qin, Li, Huang, Rong, Sheng, ZhiGuo, Cao, Dong, Zhang, ZhaoQiang, Lin, Li, Zhang, ChunZhi, Zhu, BenZhan. Mechanism of synergistic DNA damage induced by caffeic acid phenethyl ester (CAPE) and Cu(II): Competitive binding between CAPE and DNA with Cu(II)/Cu(I). FREE RADICAL BIOLOGY AND MEDICINE[J]. 2020, 159: 107-118, http://dx.doi.org/10.1016/j.freeradbiomed.2020.06.033.
[32] Huang, Rong, Zhu, JianQiang, Tang, Miao, Huang, ChunHua, Zhang, ZhiHui, Sheng, ZhiGuo, Liu, Sijin, Zhu, BenZhan. Unexpected reversible and controllable nuclear uptake and efflux of the DNA "light-switching'' Ru(II)-polypyridyl complex in living cells via ion-pairing with chlorophenolate counter-anions. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2020, 8(45): 10327-10336, https://www.webofscience.com/wos/woscc/full-record/WOS:000592062800018.
[33] Wu, Bingdang, Zhang, Guoyang, Zhang, Li, Song, Xiaojie, Zhang, Shujuan, Zhu, BenZhan. Key factors in the ligand effects on the photo redox cycling of aqueous iron species. GEOCHIMICA ET COSMOCHIMICA ACTA[J]. 2020, 281: 1-11, http://dx.doi.org/10.1016/j.gca.2020.05.004.
[34] Zhu, Benzhan, Shen, Chen, Sheng, Zhiguo. Mechanism of the Endocrine-Disruptive Effects of Low-Dose Bisphenol A via Transmembrane Receptor. PROGRESS IN CHEMISTRY[J]. 2019, 31(1): 167-179, http://dx.doi.org/10.7536/PC180414.
[35] Jie, Jialong, Xia, Ye, Huang, ChunHua, Zhao, Hongmei, Yang, Chunfan, Liu, Kunhui, Song, Di, Zhu, BenZhan, Su, Hongmei. Sulfur-centered hemi-bond radicals as active intermediates in S-DNA phosphorothioate oxidation. NUCLEIC ACIDS RESEARCH[J]. 2019, 47(22): 11514-11526, https://www.webofscience.com/wos/woscc/full-record/WOS:000522289000008.
[36] Sheng, Zhiguo, Wang, Cong, Ren, Furong, Liu, Yuxiang, Zhu, Benzhan. Molecular mechanism of endocrine-disruptive effects induced by Bisphenol A: The role of transmembrane G-protein estrogen receptor 1 and integrin alpha v beta 3. JOURNALOFENVIRONMENTALSCIENCES[J]. 2019, 75: 1-13, http://dx.doi.org/10.1016/j.jes.2018.05.002.
[37] Zhu, Ben Zhan. Mechanism of Unusual H2O2-Independent but Superoxide-Dependent Production of Hydroxyl Radicals and DNA Damages by Mn(III)-activated Hydrazine-derived Drugs and Environmental Carcinogens. FREE RADICAL BIOLOGY AND MEDICINEnull. 2019, 145: S56-S56, http://dx.doi.org/10.1016/j.freeradbiomed.2019.10.145.
[38] Zhiguo Sheng, Cong Wang, Furong Ren, Yuxiang Liu, Benzhan Zhu. Molecular mechanism of endocrine-disruptive effects induced by Bisphenol A:The role of transmembrane G-protein estrogen receptor 1 and integrin ανβ3. 环境科学学报:英文版[J]. 2019, 1-13, http://lib.cqvip.com/Qikan/Article/Detail?id=6100097546.
[39] Xie, LinNa, Shao, Jie, Huang, ChunHua, Li, Feng, Xu, Dan, Kalyanaraman, Balaraman, Zhu, BenZhan. An unusual double radical homolysis mechanism for the unexpected activation of the aldoxime nerve-agent antidotes by polyhalogenated quinoid carcinogens under normal physiological conditions. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2019, 130: 1-7, http://dx.doi.org/10.1016/j.freeradbiomed.2018.10.425.
[40] Xu, Dan, Huang, ChunHua, Xie, LinNa, Shao, Bo, Mao, Li, Shao, Jie, Kalyanaraman, Balaraman, Zhu, BenZhan. Mechanism of unprecedented hydroxyl radical production and site-specific oxidative DNA damage by photoactivation of the classic arylhydroxamic acid carcinogens. CARCINOGENESIS[J]. 2019, 40(9): 1153-1163, [41] Sheng Zhiguo, Wang Cong, Ren Furong, Liu Yuxiang, Zhu Benzhan. Molecular mechanism of endocrine-disruptive effects induced by Bisphenol A: The role of transmembrane G-protein estrogen receptor 1 and integrin αvβ3. JOURNAL OF ENVIRONMENTAL SCIENCES[J]. 2019, 75: 1-13, http://dx.doi.org/10.1016/j.jes.2018.05.002.
[42] Huang, Rong, Tang, Miao, Huang, ChunHua, Chao, XiJuan, Yan, ZhuYing, Shao, Jie, Zhu, BenZhan. What Are the Major Physicochemical Factors in Determining the Preferential Nuclear Uptake of the DNA "Light-Switching" Ru(II)-Polypyridyl Complex in Live Cells via Ion-Pairing with Chlorophenolate Counter-Anions?. JOURNAL OF PHYSICAL CHEMISTRY LETTERS[J]. 2019, 10(14): 4123-4128, [43] Zhu, Ben Zhan. Metal-independent Production of Hydroxyl Radicals from Sulfate Radical Under Weakly Acidic and Alkaline Conditions: A Direct and Unequivocal ESR Secondary Radical Spin-trapping Study. FREE RADICAL BIOLOGY AND MEDICINEnull. 2019, 145: S55-S55, http://dx.doi.org/10.1016/j.freeradbiomed.2019.10.144.
[44] Qin, Li, Huang, ChunHua, Xu, Dan, Xie, LinNa, Shao, Jie, Mao, Li, Kalyanaraman, Balaraman, Zhu, BenZhan. Molecular mechanism for the activation of the anti-tuberculosis drug isoniazid by Mn(III): First detection and unequivocal identification of the critical N-centered isoniazidyl radical and its exact location. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2019, 143: 232-239, http://dx.doi.org/10.1016/j.freeradbiomed.2019.07.012.
[45] Sheng, ZhiGuo, Shen, Chen, Fan, RuiMei, Chao, XiJuan, Liu, YuXiang, Zhu, BenZhan. The Critical Role of X Chromosome-Linked Inhibitor of Apoptosis (XIAP) in Differential Synergism Induced by Pentachlorophenol and Copper-1,10-Phenanthroline Complex in Normal and Cancer Liver Cells. TOXICOLOGICAL SCIENCES[J]. 2019, 168(2): 339-348, https://www.webofscience.com/wos/woscc/full-record/WOS:000465223200006.
[46] Chao, XiJuan, Tang, Miao, Huang, Rong, Huang, ChunHua, Shao, Jie, Yan, ZhuYing, Zhu, BenZhan. Targeted live-cell nuclear delivery of the DNA 'light-switching' Ru(II) complex via ion-pairing with chlorophenolate counter-anions: the critical role of binding stability and lipophilicity of the ion-pairing complexes. NUCLEICACIDSRESEARCH[J]. 2019, 47(20): 10520-10528, https://www.webofscience.com/wos/woscc/full-record/WOS:000501735500014.
[47] Huang, Rong, Huang, ChunHua, Shao, Jie, Zhu, BenZhan. Enantioselective and Differential Fluorescence Lifetime Imaging of Nucleus and Nucleolus by the Two Enantiomers of Chiral Os(II) Polypyridyl Complex. JOURNAL OF PHYSICAL CHEMISTRY LETTERS[J]. 2019, 10(19): 5909-5916, https://www.webofscience.com/wos/woscc/full-record/WOS:000489189500036.
[48] Zhu, Ben Zhan. A Novel Free Radical Pathway for the Formation of Unprecedented Nitrogerpcentered Chirat DNA Adducts by the Classic Chenrical Hydroxanne Acid Careinogen in Vitro and in Vivo. FREE RADICAL BIOLOGY AND MEDICINEnull. 2019, 145: S55-S55, https://www.webofscience.com/wos/woscc/full-record/WOS:000496777400129.
[49] 朱本占, 沈忱, 盛治国. 膜受体介导双酚A低剂量内分泌干扰效应的分子机制. 化学进展[J]. 2019, 167-179, https://manu56.magtech.com.cn/progchem/CN/10.7536/PC180414.
[50] Wu, Zihao, Chen, Chunyan, Zhu, BenZhan, Huang, ChunHua, An, Taicheng, Meng, Fangang, Fang, Jingyun. Reactive Nitrogen Species Are Also Involved in the Transformation of Micropollutants by the UV/Monochloramine Process. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2019, 53(19): 11142-11152, https://www.webofscience.com/wos/woscc/full-record/WOS:000488993500011.
[51] Zhu, Ben Zhan. Unexpected Activation of N-Alkyl Hydroxamic Acids to Produce Reactive N-centered Free Radicals and DNA Damages by Carcinogenic Chlorinated Quinones under Normal Physiological Conditions. FREE RADICAL BIOLOGY AND MEDICINEnull. 2019, 145: S56-S56, http://dx.doi.org/10.1016/j.freeradbiomed.2019.10.146.
[52] Zhu, BenZhan. Unexpected hydroxyl radical production and DNA damage via UV and sunlight irradiation of the genotoxic hydroxamic acid intermediate of polyaromatic amine carcinogen. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETYnull. 2018, 256: https://www.webofscience.com/wos/woscc/full-record/WOS:000447609100003.
[53] Zhu, BenZhan. Targeted live-cell nuclear delivery of the DNA 'light-switching' Ru(ii) complex via ion-pairing with chlorophenolate counter-anions: the critical role of binding stability and lipophilicity of the ion-paring complexes. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETYnull. 2018, 256: https://www.webofscience.com/wos/woscc/full-record/WOS:000447609101159.
[54] Zhu, BenZhan. Mechanism of the synergistic DNA damage and unusual hydroxyl radical production by the non-enzymatic activation of the anti-tuberculosis drug isoniazid by Mn(III). FREE RADICAL BIOLOGY AND MEDICINEnull. 2018, 120: S112-S113, https://www.webofscience.com/wos/woscc/full-record/WOS:000432836500356.
[55] Zhu, BenZhan. An unexpected free radical mechanism for DNA damage by the carcinogenic arylhydroxamic acid via sunlight irradiation. FREE RADICAL BIOLOGY AND MEDICINEnull. 2018, 120: S113-S113, https://www.webofscience.com/wos/woscc/full-record/WOS:000432836500358.
[56] Zhu, BenZhan. An unexpected double radical homolysis mechanism for the reactions between the pyridinium aldoxime nerve agent antidotes and polyhalogenated quinones under normal physiological conditions. FREE RADICAL BIOLOGY AND MEDICINEnull. 2018, 120: S113-S114, https://www.webofscience.com/wos/woscc/full-record/WOS:000432836500359.
[57] Zhu, Benzhan, Xiao, Xuan, Chao, Xijuan, Tang, Miao, Huang, Rong, Shao, Jie. Investigation of the Mechanism of Cellular Uptake, Distribution and Toxicity of the DNA 'Light-Switch' Ru(II) Polypyridyl Complexes. PROGRESS IN CHEMISTRYnull. 2018, 30(12): 1975-1991, http://ir.rcees.ac.cn/handle/311016/40973.
[58] Zhu, BenZhan. Site-specific production of hydroxyl radicals and synergistic DNA damage induced by the non-enzymatic activation of the anti-tuberculosis drug isoniazid by Cu(II). ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETYnull. 2018, 256: https://www.webofscience.com/wos/woscc/full-record/WOS:000447609106306.
[59] 任福荣, 肖璇, 谢琳娜, 徐丹, 邵杰, 黄春华, 朱本占. 醛肟类神经性毒剂防治药物的新型解毒分子作用机制. 中国科学:化学[J]. 2018, 48(10): 1247-1259, https://www.sciengine.com/doi/10.1360/N032018-00084.
[60] Zhu, Benzhan, Shen, Chen, Gao, Huiying, Zhu, Liya, Shao, Jie, Mao, Li. Intrinsic chemiluminescence production from the degradation of haloaromatic pollutants during environmentally-friendly advanced oxidation processes: Mechanism, structure-activity relationship and potential applications. JOURNAL OF ENVIRONMENTAL SCIENCES[J]. 2017, 62: 68-83, http://ir.rcees.ac.cn/handle/311016/39342.
[61] 朱本占, 谢琳娜, 沈忱, 高慧颖, 朱丽雅, 毛莉. 卤代芳烃化学发光的结构效应、分子机制及其应用. 化学进展[J]. 2017, 29(9): 930-942, http://ir.rcees.ac.cn/handle/311016/38033.
[62] Zhu, BenZhan. Site-specific Production of Hydroxyl Radicals and Synergistic DNA Damage Induced by the Non-enzymatic Activation of the Anti-tuberculosis Drug Isoniazid by Cu(II). FREE RADICAL BIOLOGY AND MEDICINEnull. 2017, 112: 68-68, https://www.webofscience.com/wos/woscc/full-record/WOS:000415805100110.
[63] Zhu, Benzhan, Shen, Chen, Gao, Huiying, Zhu, Liya, Shao, Jie, Mao, Li. Intrinsic chemiluminescence production from the degradation of haloaromatic pollutants during environmentally-friendly advanced oxidation processes: Mechanism, structure-activity relationship and potential applications. JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA[J]. 2017, 62(12): 68-83, http://lib.cqvip.com/Qikan/Article/Detail?id=72747566504849554950484857.
[64] Gao, HuiYing, Mao, Li, Li, Feng, Xie, LinNa, Huang, ChunHua, Shao, Jie, Shao, Bo, Kalyanaraman, Balaraman, Zhu, BenZhan. Mechanism of Intrinsic Chemiluminescence Production from the Degradation of Persistent Chlorinated Phenols by the Fenton System: A Structure-Activity Relationship Study and the Critical Role of Quinoid and Semiquinone Radical Intermediates. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2017, 51(5): 2934-2943, http://ir.rcees.ac.cn/handle/311016/39356.
[65] Benzhan Zhu, Chen Shen, Huiying Gao, Liya Zhu, Jie Shao, Li Mao. Intrinsic chemiluminescence production from the degradation of haloaromatic pollutants during environmentally-friendly advanced oxidation processes: Mechanism, structure-activity relationship and potential applications. 环境科学学报:英文版[J]. 2017, 68-83, http://lib.cqvip.com/Qikan/Article/Detail?id=72747566504849554950484857.
[66] 徐丹, 朱本占. 紫外照射多环芳胺致癌性代谢产物-异羟肟酸导致羟基自由基生成及DNA损伤机制研究. 第十五届全国光化学学术讨论会会议论文集null. 2017, 2-, http://ir.rcees.ac.cn/handle/311016/40026.
[67] Zhu, BenZhan. Nitroxide Radical Production from Hydroxamic Acids and Carcinogenic Halogenated Quinones via an Unexpected Nitrogen-centered Radical Intermediate Pathway. FREE RADICAL BIOLOGY AND MEDICINEnull. 2017, 112: 66-67, https://www.webofscience.com/wos/woscc/full-record/WOS:000415805100107.
[68] Shao, Bo, Mao, Li, Qu, Na, Wang, YaFen, Gao, HuiYing, Li, Feng, Qin, Li, Shao, Jie, Huang, ChunHua, Xu, Dan, Xie, LinNa, Shen, Chen, Zhou, Xiang, Zhu, BenZhan. Mechanism of synergistic DNA damage induced by the hydroquinone metabolite of brominated phenolic environmental pollutants and Cu(II): Formation of DNA-Cu complex and site-specific production of hydroxyl radicals. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2017, 104: 54-63, http://dx.doi.org/10.1016/j.freeradbiomed.2016.12.050.
[69] Zhu, BenZhan. The Critical Role of Quinone-Enoxy Radicals in the Production of the More Mutagenic dIz from DNA by Carcinogenic Halogenated Quinones and Hydroperoxides. FREE RADICAL BIOLOGY AND MEDICINEnull. 2017, 112: 67-68, https://www.webofscience.com/wos/woscc/full-record/WOS:000415805100109.
[70] Zhu, BenZhan. Metal-independent Hydroxyl Radical Production and DNA Damage by Sunlight-Irradiation of Hydroxamic Acid Carcinogens. FREE RADICAL BIOLOGY AND MEDICINEnull. 2017, 112: 67-67, https://www.webofscience.com/wos/woscc/full-record/WOS:000415805100108.
[71] HuiYing Gao, Li Mao, Feng Li, LinNa Xie, ChunHua Huang, Jie Shao, Bo Shao, Balaraman Kalyanaraman, BenZhan Zhu. Mechanism of Intrinsic Chemiluminescence Production from the Degradation of Persistent Chlorinated Phenols by Fenton System: A Structure-Activity Relationship Study and the Critical Role of Quinoid and Semiquinone Radical Intermediates. ENVIRONMENTAL SCIENCE & TECHNOLOGY. 2017, 51(5): 2934-2943, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806603/.
[72] Zhu, Benzhan, Xie, Linna, Shen, Chen, Gao, Huiying, Zhu, Liya, Mao, Li. Chemiluminescence Generation from Haloaromatic Pollutants: Structure-Activity Relationship, Molecular Mechanism and Potential Applications. PROGRESS IN CHEMISTRY[J]. 2017, 29(9): 930-942, http://ir.rcees.ac.cn/handle/311016/39271.
[73] Xie, LinNa, Huang, ChunHua, Xu, Dan, Li, Feng, Zhu, JunGe, Shen, Chen, Shao, Bo, Gao, HuiYing, Kalyanaraman, Balaraman, Zhe, BenZhan. Unusual Double Beckmann Fragmentation Reaction under Physiological Conditions. JOURNAL OF ORGANIC CHEMISTRY[J]. 2017, 82(24): 13084-13092, http://ir.rcees.ac.cn/handle/311016/39453.
[74] Zhu, BenZhan, Shao, Jie. Molecular Mechanism for the Production of the More Mutagenic DIz from DNA by Halogenated Quinoid Carcinogens and Hydroperoxides: The Critical Role of Quinone-Enoxy Radicals. FREE RADICAL BIOLOGY AND MEDICINEnull. 2016, 100: S33-S33, https://www.webofscience.com/wos/woscc/full-record/WOS:000444355800046.
[75] Zhu, BenZhan, Qin, Li. Non-Enzymatic Radical Activation of the Potent Anti-Tubercular Isoniazid by Cu(II). FREE RADICAL BIOLOGY AND MEDICINEnull. 2016, 100: S34-S34, https://www.webofscience.com/wos/woscc/full-record/WOS:000444355800049.
[76] 朱本占, 邵杰. 致癌性卤代醌介导的新型自由基反应诱导DNA氧化损伤的机理研究. 中国化学会第30届学术年会摘要集-第二十六分会:环境化学null. 2016, 1-, http://ir.rcees.ac.cn/handle/311016/39988.
[77] Gao, HuiYing, Mao, Li, Shao, Bo, Huang, ChunHua, Zhu, BenZhan. Why Does 2,3,5,6-Tetrachlorophenol Generate the Strongest Intrinsic Chemiluminescence among All Nineteen Chlorophenolic Persistent Organic Pollutants during Environmentally-friendly Advanced Oxidation Process?. SCIENTIFIC REPORTS[J]. 2016, 6: http://ir.rcees.ac.cn/handle/311016/35983.
[78] Zhu, BenZhan, Xu, Dan, Huang, ChunHua. Hydroxyl Radical Production and DNA Damage via Photolysis by Sunlight of the Genotoxic Hydroxamic Acid Intermediate of Polyaromatic Amine Carcinogen. FREE RADICAL BIOLOGY AND MEDICINEnull. 2016, 100: S32-S32, https://www.webofscience.com/wos/woscc/full-record/WOS:000444355800043.
[79] Zhu, BenZhan, Chao, XiJuan, Huang, ChunHua, Li, Yan. Delivering the cell-impermeable DNA 'light-switching' Ru(II) complexes preferentially into live-cell nucleus via an unprecedented ion-pairing method. CHEMICAL SCIENCE[J]. 2016, 7(7): 4016-4023, http://ir.rcees.ac.cn/handle/311016/35831.
[80] Zhu, BenZhan, Liu, YuXiang. Mechanism of DNA Double-Strand Cleavage by a New Chlorination Disinfection Byproduct Trichloro-1,4-Benzoquinone and H2O2 and Protection by Thiol-Containing Drugs. FREE RADICAL BIOLOGY AND MEDICINEnull. 2016, 100: S116-S116, https://www.webofscience.com/wos/woscc/full-record/WOS:000444355800261.
[81] Zhu Benzhan, Shao Bo, Mao Li, Gao Huiying. Intrinsic Chemiluminescence Production during Environmentally-friendly Advanced Oxidation of Halogenated Aromatics and Its Applications. ACTA CHIMICA SINICA[J]. 2016, 74(7): 557-564, http://ir.rcees.ac.cn/handle/311016/35880.
[82] Zhu, BenZhan, Mao, Li. Molecular Mechanism of an Unexpected Novel Antioxidant-Like Activity for the Classic Copper-Chelating Drug Penicillamine. FREE RADICAL BIOLOGY AND MEDICINEnull. 2016, 100: S115-S116, https://www.webofscience.com/wos/woscc/full-record/WOS:000444355800260.
[83] Qu, Na, Li, Feng, Shao, Bo, Shao, Jie, Zhai, Guijin, Wang, Fuyi, Zhu, BenZhan. The Unexpected and Exceptionally Facile Chemical Modification of the Phenolic Hydroxyl Group of Tyrosine by Polyhalogenated Quinones under Physiological Conditions. CHEMICAL RESEARCH IN TOXICOLOGY[J]. 2016, 29(10): 1699-1705, http://ir.rcees.ac.cn/handle/311016/35962.
[84] 朱本占, 徐丹. 多环芳胺致癌的新型自由基机制:光致羟基自由基的生成及DNA损伤. 中国化学会第30届学术年会摘要集-第二十六分会:环境化学null. 2016, 1-, http://ir.rcees.ac.cn/handle/311016/39943.
[85] Zhu Benzhan, Shao Bo, Mao Li, Gao Huiying. Intrinsic Chemiluminescence Production during Environmentally-friendly Advanced Oxidation of Halogenated Aromatics and Its Applications. ACTA CHIMICA SINICA[J]. 2016, 74(7): 557-564, http://ir.rcees.ac.cn/handle/311016/35880.
[86] Zhu, BenZhan, Huang, ChunHua. Synergism between Tetrachlorocatechol and NaN3: Detection and Identification of Two Novel Azido-Substituted Chloro-O-Semiquinone Radicals. FREE RADICAL BIOLOGY AND MEDICINEnull. 2016, 100: S34-S34, https://www.webofscience.com/wos/woscc/full-record/WOS:000444355800048.
[87] Zhu, BenZhan, Xu, Dan, Huang, ChunHua. An Unexpected New Molecular Mechanism for the Formation of Nitroxide Radical from Hydroxamic Acids and Polyhalogenated Quinoid Carcinogens. FREE RADICAL BIOLOGY AND MEDICINEnull. 2016, 100: S33-S33, [88] Li, Feng, Huang, ChunHua, Xie, LinNa, Qu, Na, Shao, Jie, Shao, Bo, Zhu, BenZhan. An Exceptionally Facile Two-Step Structural Isomerization and Detoxication via a Water-Assisted Double Lossen Rearrangement. SCIENTIFIC REPORTS[J]. 2016, 6: http://ir.rcees.ac.cn/handle/311016/35799.
[89] Zhu, BenZhan, Liu, YuXiang. Mechanism of Protection by the Heavy Metal Poisoning Antidote 2,3-Dimercaptosuccinic Acid Against Copper-Induced DNA Cleavage Via Forming A Redox-Inactive Copper Complex. FREE RADICAL BIOLOGY AND MEDICINEnull. 2016, 100: S116-S116, https://www.webofscience.com/wos/woscc/full-record/WOS:000444355800262.
[90] 朱本占, 黄春华. 致癌性多环芳胺诱导形成DNA加合物的新机制:自由基或氮正离子. 中国化学会第30届学术年会摘要集-第二十六分会:环境化学null. 2016, 1-, http://ir.rcees.ac.cn/handle/311016/39987.
[91] Ben-Zhan Zhu. Delivering the cell-impermeable DNA ‘light-switch’ Ru(II) complexes preferentially into live-cell nucleus via an unprecedented ion-pairing method. Chem. Sci.. 2016, [92] Zhu, BenZhan, Chao, XiJuan. Redirecting Ru(II)-Complex Into Live-Cell Nucleus for Enantioselective DNA-Imaging and Photosensitizing Via Simple Yin-Yang Ion-Pairing. FREE RADICAL BIOLOGY AND MEDICINEnull. 2016, 100: S33-S34, https://www.webofscience.com/wos/woscc/full-record/WOS:000444355800047.
[93] Mao, Li, Liu, YuXiang, Huang, ChunHua, Gao, HuiYing, Kalyanaraman, Balaraman, Zhu, BenZhan. Intrinsic Chemiluminescence Generation during Advanced Oxidation of Persistent Halogenated Aromatic Carcinogens. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2015, 49(13): 7940-7947, http://dx.doi.org/10.1021/acs.est.5b01227.
[94] Zhu, BenZhan, Hollenberg, Paul F. Chemical Toxicology in China: A Special Issue. CHEMICAL RESEARCH IN TOXICOLOGYnull. 2015, 28(3): 279-280, https://www.webofscience.com/wos/woscc/full-record/WOS:000351326400001.
[95] Shan, GuoQiang, Yu, Ao, Zhao, ChuanFang, Huang, ChunHua, Zhu, LingYan, Zhu, BenZhan. A Combined Experimental and Computational Investigation on the Unusual Molecular Mechanism of the Lossen Rearrangement Reaction Activated by Carcinogenic Halogenated Quinones. JOURNAL OF ORGANIC CHEMISTRY[J]. 2015, 80(1): 180-189, http://dx.doi.org/10.1021/jo5022713.
[96] 朱本占, 刘玉祥, 任福荣, 黄春华. 致癌性卤代醌与有机氢过氧化物不依赖金属分解的分子机制及其潜在生物学意义. 中国科学:化学[J]. 2015, 45(7): 692-702, http://ir.rcees.ac.cn/handle/311016/33177.
[97] Ben-Zhan Zhu. Different modes of synergistic toxicities between metam/copper (II) and metam/zinc (II) in HepG2 cells: apoptosis vs. necrosis.. Environ. Toxicol.. 2015, [98] 朱本占. 一类非同寻常的二次Lossen 重排反应: 异羟肟酸的新型解毒分子作用机制. 化学学报. 2015, [99] Ben-Zhan Zhu. Molecular mechanism of metal-independent decomposition of organic hydroperoxides by the halogenated quinoid carcinogens and the potential biological implications.. Chem. Res. Toxicol.. 2015, [100] Zhu Benzhan, Shao Bo, Li Feng, Liu Yuxiang, Huang Chunhua. An Unusual Double Lossen Rearrangement Reaction: The Novel Molecular Detoxication Mechanism for Hydroxamic Acids. ACTA CHIMICA SINICA[J]. 2015, 73(8): 765-769, http://ir.rcees.ac.cn/handle/311016/32513.
[101] Zhu Benzhan, Shao Bo, Li Feng, Liu Yuxiang, Huang Chunhua. An Unusual Double Lossen Rearrangement Reaction: The Novel Molecular Detoxication Mechanism for Hydroxamic Acids. ACTA CHIMICA SINICA[J]. 2015, 73(8): 765-769, http://ir.rcees.ac.cn/handle/311016/32513.
[102] Huang, ChunHua, Ren, FuRong, Shan, GuoQiang, Qin, Hao, Mao, Li, Zhu, BenZhan. Molecular Mechanism of Metal-Independent Decomposition of Organic Hydroperoxides by Halogenated Quinoid Carcinogens and the Potential Biological Implications. CHEMICAL RESEARCH IN TOXICOLOGY[J]. 2015, 28(5): 831-837, http://ir.rcees.ac.cn/handle/311016/32623.
[103] 朱本占, 任福荣, 毛莉, 高慧颖, 刘庆林, 刘蒲. 依赖于羟基自由基的两次化学发光产生体系:致癌性多卤代醌与过氧化氢. 科学通报[J]. 2015, 60(20): 1855-1863, http://ir.rcees.ac.cn/handle/311016/33174.
[104] Ben-Zhan Zhu. A combined experimental and computational investigation on the unusual molecular mechanism of Lossen rearrangement reaction activated by the carcinogenic halogenated quinones.. J. Org. Chem.. 2015, [105] 刘庆林, 覃浩, 黄春华, 刘蒲, 朱本占. 致癌性卤代醌介导的脂质氢过氧化物分解的分子机制. 环境化学[J]. 2014, 33(10): 1637-1644, http://hjhx.rcees.ac.cn/article/doi/10.7524/j.issn.0254-6108.2014.10.016.
[106] 黄春华, 朱本占. 四氯邻苯二酚与叠氮钠的协同毒性的分子机理:两种叠氮基-O-半醌自由基和一种独特的缩环产物的检测和鉴定. 中国化学会第29届学术年会——第20分会:环境与健康null. 2014, http://ir.rcees.ac.cn/handle/311016/24889.
[107] 黄春华, 朱本占. 四氯邻苯二酚与叠氮钠的协同毒性分子机理的质谱研究. 中国化学会首届全国质谱分析学术研讨会null. 2014, http://ir.rcees.ac.cn/handle/311016/24890.
[108] Zhao, Bailin, Yang, Ying, Wang, Xiaoli, Chong, Zechen, Yin, Ruichuan, Song, ShuHui, Zhao, Chao, Li, Cuiping, Huang, Hua, Sun, BaoFa, Wu, Danni, Jin, KangXuan, Song, Maoyong, Zhu, BenZhan, Jiang, Guibin, Danielsen, Jannie M Rendtlew, Xu, GuoLiang, Yang, YunGui, Wang, Hailin. Redox-active quinones induces genome-wide DNA methylation changes by an iron-mediated and Tet-dependent mechanism. NUCLEIC ACIDS RESEARCH[J]. 2014, 42(3): 1593-1605, http://www.irgrid.ac.cn/handle/1471x/936521.
[109] 毛莉, 朱本占. 经典铜络合剂青霉胺的一种新型类抗氧化剂特性研究. 中国化学会第29届学术年会——第20分会:环境与健康null. 2014, http://ir.rcees.ac.cn/handle/311016/24922.
[110] Li, Yan, Huang, ChunHua, Liu, YuXiang, Mao, Li, Zhu, BenZhan. Detoxifying Polyhalogenated Catechols through a Copper-Chelating Agent by Forming Stable and Redox-Inactive Hydrogen-Bonded Complexes with an Unusual Perpendicular Structure. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2014, 20(40): 13028-13033, http://www.irgrid.ac.cn/handle/1471x/936417.
[111] 谢琳娜, 朱本占. 醛肟对四氯苯醌新型解毒机制:非同寻常的连续两次贝克曼重排反应. 中国化学会第29届学术年会——第20分会:环境与健康null. 2014, http://ir.rcees.ac.cn/handle/311016/24944.
[112] 黄春华, 朱本占. 一种新型的氮氧自由基产生机理的质谱研究. 中国化学会首届全国质谱分析学术研讨会null. 2014, http://ir.rcees.ac.cn/handle/311016/24892.
[113] 黄春华, 朱本占. 一类新型自由基均裂重排机理的质谱研究. 中国化学会首届全国质谱分析学术研讨会null. 2014, http://ir.rcees.ac.cn/handle/311016/24891.
[114] 邵杰, 朱本占. 致癌性卤代醌介导的氢过氧化物分解反应诱导新型DNA氧化损伤的机理研究. 中国化学会第29届学术年会——第20分会:环境与健康null. 2014, http://ir.rcees.ac.cn/handle/311016/24929.
[115] Shan, Guoqiang, Ye, Minqiang, Zhu, Benzhan, Zhu, Lingyan. Enhanced cytotoxicity of pentachlorophenol by perfluorooctane sulfonate or perfluorooctanoic acid in HepG2 cells. CHEMOSPHERE[J]. 2013, 93(9): 2101-2107, http://dx.doi.org/10.1016/j.chemosphere.2013.07.054.
[116] Ben-Zhan Zhu. Ofloxacin induces NADPH oxidase-driven ROS accumulation via β1 integrin-EGFR-Rac1 pathway in microencapsulated chondrocytes. Toxicol. Appl. Pharmacol.. 2013, [117] 李岩, 朱本占. 五氯酚与铜-邻菲罗啉配合物协同毒性机理的研究:脂溶性三元络合物的生成与鉴定. 第七届全国环境化学学术大会null. 2013, http://ir.rcees.ac.cn/handle/311016/29606.
[118] Sheng, ZhiGuo, Li, Yan, Fan, RuiMei, Chao, XiJuan, Zhu, BenZhan. Lethal synergism between organic and inorganic wood preservatives via formation of an unusual lipophilic ternary complex. TOXICOLOGY AND APPLIED PHARMACOLOGY[J]. 2013, 266(3): 335-344, http://dx.doi.org/10.1016/j.taap.2012.11.013.
[119] 邵杰, 朱本占. 致癌性卤代醌和过氧化氢诱导DNA氧化损伤的机理研究. 第七届全国环境化学学术大会null. 2013, http://ir.rcees.ac.cn/handle/311016/29614.
[120] 黄春华, 朱本占. 四氯邻苯二酚与叠氮钠的协同毒性分子机理:两种活性叠氮基-O-半醌自由基和一种独特的缩环产物的检测和鉴定. 第七届全国环境化学学术大会null. 2013, http://ir.rcees.ac.cn/handle/311016/29600.
[121] Huang, ChunHua, Shan, GuoQiang, Mao, Li, Kalyanaraman, Balaraman, Qin, Hao, Ren, FuRong, Zhu, BenZhan. The first purification and unequivocal characterization of the radical form of the carbon-centered quinone ketoxy radical adduct. CHEMICAL COMMUNICATIONS[J]. 2013, 49(57): 6436-6438, http://www.irgrid.ac.cn/handle/1471x/844461.
[122] Qin, Hao, Huang, ChunHua, Mao, Li, Xia, HaiYing, Kalyanaraman, Balaraman, Shao, Jie, Shan, GuoQiang, Zhu, BenZhan. Molecular mechanism of metal-independent decomposition of lipid hydroperoxide 13-HPODE by halogenated quinoid carcinogens. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2013, 63: 459-466, http://dx.doi.org/10.1016/j.freeradbiomed.2013.05.008.
[123] Sheng, ZhiGuo, Huang, Wei, Liu, YuXiang, Zhu, BenZhan. Bisphenol A at a low concentration boosts mouse spermatogonial cell proliferation by inducing the G protein-coupled receptor 30 expression. TOXICOLOGY AND APPLIED PHARMACOLOGY[J]. 2013, 267(1): 88-94, http://dx.doi.org/10.1016/j.taap.2012.12.014.
[124] 朱本占, 夏海英, 覃浩, 单国强, 黄春华, 任福荣, 邵杰, 曲娜. 一种新型以碳为中心的醌酮自由基的检测和鉴定. 科学通报[J]. 2013, 12(1): 1140-1146, http://www.irgrid.ac.cn/handle/1471x/930111.
[125] Yin, Ruichuan, Zhang, Dapeng, Song, Yuling, Zhu, BenZhan, Wang, Hailin. Potent DNA damage by polyhalogenated quinones and H2O2 via a metal-independent and Intercalation-enhanced oxidation mechanism. SCIENTIFIC REPORTS[J]. 2013, 3: http://dx.doi.org/10.1038/srep01269.
[126] 毛莉, 朱本占. 持久性卤代芳烃致癌物的高级氧化过程中产生的内源性化学发光机理及其应用. 第七届全国环境化学学术大会null. 2013, http://ir.rcees.ac.cn/handle/311016/29549.
[127] Duan, Huawei, He, Zhini, Ma, Junxiang, Zhang, Bo, Sheng, Zhiguo, Bin, Ping, Cheng, Juan, Niu, Yong, Dong, Haiyan, Lin, Han, Dai, Yufei, Zhu, Benzhan, Chen, Wen, Xiao, Yongmei, Zheng, Yuxin. Global and MGMT promoter hypomethylation independently associated with genomic instability of lymphocytes in subjects exposed to high-dose polycyclic aromatic hydrocarbon. ARCHIVESOFTOXICOLOGY[J]. 2013, 87(11): 2013-2022, https://www.webofscience.com/wos/woscc/full-record/WOS:000325700300011.
[128] Shao, Jie, Huang, ChunHua, Kalyanaraman, Balaraman, Zhu, BenZhan. Potent methyl oxidation of 5-methyl-2 '-deoxycytidine by halogenated quinoid carcinogens and hydrogen peroxide via a metal-independent mechanism. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2013, 60: 177-182, http://dx.doi.org/10.1016/j.freeradbiomed.2013.01.010.
[129] Wang, Jing, Yu, Shouyi, Jiao, Shouhai, Lv, Xiaowen, Ma, Min, Zhu, Benzhan, Du, Yuguo. Characterization of TCHQ-induced genotoxicity and mutagenesis using the pSP189 shuttle vector in mammalian cells. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS[J]. 2012, 729(1-2): 16-23, http://dx.doi.org/10.1016/j.mrfmmm.2011.08.010.
[130] Zhu, BenZhan, Mao, Li, Huang, ChunHua, Qin, Hao, Fan, RuiMei, Kalyanaraman, Balaraman, Zhu, JunGe. Unprecedented hydroxyl radical-dependent two-step chemiluminescence production by polyhalogenated quinoid carcinogens and H2O2. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2012, 109(40): 16046-16051, http://www.irgrid.ac.cn/handle/1471x/901096.
[131] Sheng, ZhiGuo, Tang, Yuan, Liu, YuXiang, Yuan, Ye, Zhao, BaoQuan, Chao, XiJuan, Zhu, BenZhan. Low concentrations of bisphenol a suppress thyroid hormone receptor transcription through a nongenomic mechanism. TOXICOLOGY AND APPLIED PHARMACOLOGY[J]. 2012, 259(1): 133-142, http://dx.doi.org/10.1016/j.taap.2011.12.018.
[132] 朱本占, 任福荣, 夏海英, 邵杰. 不依赖于过渡金属离子的卤代醌介导的新型有机类Fenton反应机理. 生物物理学报[J]. 2012, 28(4): 324-331, http://lib.cqvip.com/Qikan/Article/Detail?id=41834881.
[133] Wang, Jing, Yu, Shouyi, Jiao, Shouhai, Lv, Xiaowen, Ma, Min, Zhu, Ben-zhan, Du, Yuguo. Characterization of TCHQ-induced genotoxicity and mutagenesis using the pSP189 shuttle vector in mammalian cells. BIOTECHNOLOGY & APPLIED MICROBIOLOGY; GENETICS & HEREDITY; TOXICOLOGY[J]. 2012, 729(1): 16-23, http://dx.doi.org/10.1016/j.mrfmmm.2011.08.010.
[134] 盛治国, 朱本占. 环境相关低剂量双酚A通过干扰整合素αvβ3介导的甲状腺素非基因组效应抑制基因转录. 中国化学会第28届学术年会null. 2012, http://ir.rcees.ac.cn/handle/311016/32142.
[135] 黄春华, 朱本占. 2;5-二氯对苯醌与N-甲基苯基异羟肟酸的自由基反应机制. 中国化学会第28届学术年会null. 2012, http://ir.rcees.ac.cn/handle/311016/31966.
[136] Sheng, Zhi-Guo, Tang, Yuan, Liu, Yu-Xiang, Yuan, Ye, Zhao, Bao-Quan, Chao, Xi-Juan, Zhu, Ben-Zhan. Low concentrations of bisphenol a suppress thyroid hormone receptor transcription through a nongenomic mechanism. PHARMACOLOGY & PHARMACY; TOXICOLOGY[J]. 2012, 259(1): 133-142, http://dx.doi.org/10.1016/j.taap.2011.12.018.
[137] 邵杰, 黄春华, 朱本占. 5-甲基胞嘧啶被卤代醌和过氧化氢氧化机理的研究. 中国化学会第28届学术年会null. 2012, http://ir.rcees.ac.cn/handle/311016/31967.
[138] 盛治国, 朱本占. 低剂量双酚A通过膜G蛋白偶联受体GPR30和雌激素受体ER-α诱导鼠精原细胞增殖. 第七次全国分析毒理学大会暨第四届分析毒理专业委员会第二次会议null. 2012, http://ir.rcees.ac.cn/handle/311016/31988.
[139] Zhu, BenZhan, Wang, Hailin. Potent DNA Damage by Polyhalogenated Quinoid Carcinogens and H2O2 via a Metal-Independent and Intercalation-Enhanced Oxidation Mechanism. FREE RADICAL BIOLOGY AND MEDICINEnull. 2012, 53: S140-S140, http://dx.doi.org/10.1016/j.freeradbiomed.2012.10.384.
[140] Zhu, BenZhan, Fan, RuiMei, Qu, Na. A Novel Mechanism for Metal-independent Hydroxyl Radical Production by Hydrogen Peroxide and Halogenated Quinones. MINI-REVIEWS IN ORGANIC CHEMISTRY[J]. 2011, 8(4): 434-437, http://ir.rcees.ac.cn/handle/311016/6983.
[141] Zhu, BenZhan, Huang, ChunHuan. Metal-independent Decomposition of Organic Hydroperoxides by Halogenated Quinones: the First Purification and Identification of the Unusual Carbon-centered Quinone Ketoxy Radical Adduct. FREE RADICAL BIOLOGY AND MEDICINEnull. 2011, 51: S152-S152, http://dx.doi.org/10.1016/j.freeradbiomed.2011.10.269.
[142] Zhu, BenZhan, Shao, Jie. Metal-independent Oxidative Modification of DNA Nulceobases Induced by Pentachlorophenol Quinoid Metabolites and Hydrogen Peroxide. FREE RADICAL BIOLOGY AND MEDICINEnull. 2011, 51: S141-S142, http://dx.doi.org/10.1016/j.freeradbiomed.2011.10.304.
[143] Zhu, BenZhan, Mao, Li. Unprecedented Hydroxyl Radical-dependent Two-step Chemiluminescence Production by Polyhalogenated Quinoid Carcinogens and Hydrogen Peroxide. FREE RADICAL BIOLOGY AND MEDICINEnull. 2011, 51: S153-S153, http://dx.doi.org/10.1016/j.freeradbiomed.2011.10.270.
[144] Wang, Yimei, Lu, Chunfeng, Sheng, Zhiguo, Liu, Gang, Fu, Ze, Zhu, Benzhan, Peng, Shuangqing. Enhanced hepatotoxicity induced by repeated exposure to polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin in combination in male rats. JOURNAL OF ENVIRONMENTAL SCIENCES[J]. 2011, 23(1): 119-124, http://lib.cqvip.com/Qikan/Article/Detail?id=36502666.
[145] Zhu, BenZhan, Mao, Li, Fan, RuiMei, Zhu, JunGe, Zhang, YingNan, Wang, Jing, Kalyanaraman, Balaraman, Frei, Balz. Ergothioneine Prevents Copper-Induced Oxidative Damage to DNA and Protein by Forming a Redox-Inactive Ergothioneine-Copper Complex. CHEMICAL RESEARCH IN TOXICOLOGY[J]. 2011, 24(1): 30-34, http://dx.doi.org/10.1021/tx100214t.
[146] Zhu, BenZhan, Ren, FuRong. Metal-independent Hydroxyl Radical Production by Halogenated Quinones and Hydrogen Peroxide: a Fluorescent Study. FREE RADICAL BIOLOGY AND MEDICINEnull. 2011, 51: S142-S142, http://dx.doi.org/10.1016/j.freeradbiomed.2011.10.306.
[147] 朱本占, 范瑞梅, 盛治国. 有机农药和含铜、锌等无机农药协同毒性作用机理. 科学通报[J]. 2011, 56(25): 2111-2118, http://lib.cqvip.com/Qikan/Article/Detail?id=39268029.
[148] Zhu, BenZhan, Huang, ChunHuan. An Unexpected Radical Pathway for the Reaction Between 2,5-Dichloro-1,4-Benzoquinone and N-Methyl Benzohydroxamic Acid. FREE RADICAL BIOLOGY AND MEDICINEnull. 2011, 51: S152-S152, http://dx.doi.org/10.1016/j.freeradbiomed.2011.10.268.
[149] Zhu, BenZhan, Qu, Na. Mild and Facile Interactions Between Tyrosine and Polyhalogenated Quinones Under Physiological Conditions. FREE RADICAL BIOLOGY AND MEDICINEnull. 2011, 51: S153-S153, http://dx.doi.org/10.1016/j.freeradbiomed.2011.10.271.
[150] Na Qu, Liang-Hong Guo, Ben-Zhan Zhu. An electrochemical biosensor for the detection of tyrosine oxidation induced by Fenton reaction. BIOSENSORS AND BIOELECTRONICS. 2011, 26(5): 2292-2296, http://dx.doi.org/10.1016/j.bios.2010.09.054.
[151] 朱本占, 毛莉, 范瑞梅, 朱俊歌. 天然抗氧化剂麦角硫因保护铜所致DNA和蛋白质氧化损伤的作用机理. 科学通报[J]. 2011, 56(27): 2283-2288, http://lib.cqvip.com/Qikan/Article/Detail?id=39613738.
[152] 朱本占, 覃浩, 黄春华. 新型羟基和醌碳自由基产生的分子机理. 波谱学杂志[J]. 2011, 28(4): 479-489, http://lib.cqvip.com/Qikan/Article/Detail?id=40264421.
[153] Zhu, BenZhan, QIn, Han. Metal-independent Decomposition of Lipid Hydroperoxide (13-HPODE) and Formation of 4-Hydroxy-2-Nonenal (4-HNE) by the Carcinogenic Halogenated Quinones. FREE RADICAL BIOLOGY AND MEDICINEnull. 2011, 51: S142-S142, http://dx.doi.org/10.1016/j.freeradbiomed.2011.10.305.
[154] ZhiGuo Sheng, BenZhan Zhu. Low Concentrations of Bisphenol A Induce Mouse Spermatogonial Cell Proliferation by G Protein–Coupled Receptor 30 and Estrogen Receptor-α. ENVIRONMENTAL HEALTH PERSPECTIVES. 2011, 119(12): 1775-1780, [155] Zhu, BenZhan, Mao, Li. A Novel Hydroxyl Radical-dependent Two-step Chemiluminescence Producing System: Polyhalogenated Quinoid Compounds and Hydrogen Peroxide. FREE RADICAL BIOLOGY AND MEDICINEnull. 2010, 49: S217-S217, http://dx.doi.org/10.1016/j.freeradbiomed.2010.10.634.
[156] Jia, Suping, Zhu, Ben-Zhan, Guo, Liang-Hong. Detection and mechanistic investigation of halogenated benzoquinone induced DNA damage by photoelectrochemical DNA sensor. 6th International Conference on Instrumental Methods of Analysisnull. 2010, http://ir.rcees.ac.cn/handle/311016/24637.
[157] Zhu, BenZhan, Mao, Li, Frei, Balz. Ergothioneine Prevents Copper-induced Oxidative Damage to DNA and Protein by Formation of a Redox-inactive Ergothioneine-copper Complex. FREE RADICAL BIOLOGY AND MEDICINEnull. 2010, 49: S205-S205, http://dx.doi.org/10.1016/j.freeradbiomed.2010.10.596.
[158] Zhu, BenZhan, Zhu, JunGe, Kalyanaraman, Balaraman. Detoxifying Carcinogenic Polyhalogenated Quinones by Hydroxamic Acids via an Unusual Double Lossen Rearrangement Mechanism. FREE RADICAL BIOLOGY AND MEDICINEnull. 2010, 49: S217-S217, http://dx.doi.org/10.1016/j.freeradbiomed.2010.10.633.
[159] Zhu, BenZhan, Mao, Li. An Unexpected Novel Antioxidant-like Activity for the Classic Copper-chelating Drug Penicillamine. FREE RADICAL BIOLOGY AND MEDICINE. 2010, 49: S205-S205, http://dx.doi.org/10.1016/j.freeradbiomed.2010.10.595.
[160] Lu, Chunfeng, Wang, Yimei, Sheng, Zhiguo, Liu, Gang, Fu, Ze, Zhao, Jing, Zhao, Jun, Yan, Xianzhong, Zhu, Benzhan, Peng, Shuangqing. NMR-based metabonomic analysis of the hepatotoxicity induced by combined exposure to PCBs and TCDD in rats. TOXICOLOGY AND APPLIED PHARMACOLOGY[J]. 2010, 248(3): 178-184, http://dx.doi.org/10.1016/j.taap.2010.07.020.
[161] Zhu, BenZhan, Zhu, JunGe, Mao, Li, Kalyanaraman, Balaraman, Shan, GuoQiang. Detoxifying carcinogenic polyhalogenated quinones by hydroxamic acids via an unusual double Lossen rearrangement mechanism. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2010, 107(48): 20686-20690, http://www.irgrid.ac.cn/handle/1471x/964199.
[162] Jia, Suping, Zhu, BenZhan, Guo, LiangHong. Detection and mechanistic investigation of halogenated benzoquinone induced DNA damage by photoelectrochemical DNA sensor. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2010, 397(6): 2395-2400, http://ir.rcees.ac.cn/handle/311016/21063.
[163] Zhu, BenZhan, Zhu, JunGe. Mechanism of Protection by Suberoylanilide Hydroxamic Acid (Vorinostat) against Tetrahalogenated Quinone-induced Cytotoxicity: Suicidal Nucleophilic Attack Coupled with Unusually Mild and Facile Double Lossen Rearrangement. FREE RADICAL BIOLOGY AND MEDICINEnull. 2010, 49: S204-S204, http://dx.doi.org/10.1016/j.freeradbiomed.2010.10.594.
[164] 朱本占. 一种新型羟基自由基产生分子机理的研究. 科学通报[J]. 2009, 1673-1680, http://lib.cqvip.com/Qikan/Article/Detail?id=30842013.
[165] Zhu, BenZhan, Shan, GuoQiang. Potential Mechanism for Pentachlorophenol-Induced Carcinogenicity: A Novel Mechanism for Metal-Independent Production of Hydroxyl Radicals. CHEMICAL RESEARCH IN TOXICOLOGY[J]. 2009, 22(6): 969-977, http://www.irgrid.ac.cn/handle/1471x/971930.
[166] Ben-Zhan Zhu. 新型羟基自由基产生分子机理的研究: 五氯酚的可能致癌机制. 《科学通报》. 2009, [167] Zhu, BenZhan, Mao, Li. A Novel Mechanism for Hydroxyl Radical-dependent Two-step Chemiluminescence Production by Halogenated Quinones and Hydrogen Peroxide. FREE RADICAL BIOLOGY AND MEDICINEnull. 2009, 47: S194-S194, https://www.webofscience.com/wos/woscc/full-record/WOS:000271988500565.
[168] Zhu, BenZhan, Shan, GuoQiang, Huang, ChunHua, Kalyanaraman, Balaraman, Mao, Li, Du, YuGuo. Metal-independent decomposition of hydroperoxides by halogenated quinones: Detection and identification of a quinone ketoxy radical. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2009, 106(28): 11466-11471, http://www.irgrid.ac.cn/handle/1471x/971911.
[169] 原野, 朱本占, 盛治国. 环境持久性污染物五氯酚和铜(Ⅱ)-邻菲罗啉通过诱导ROS蓄积对人肝细胞产生协同毒性作用. 中国毒理学会第五次全国学术大会论文集null. 2009, http://ir.rcees.ac.cn/handle/311016/37315.
[170] 任福荣, 朱本占. 卤代苯醌/过氧化氢反应体系的羟基自由基的荧光检测,反应动力学及作用机理研究. 第五届全国环境化学大会会议论文集null. 2008, 416-, http://ir.rcees.ac.cn/handle/311016/5876.
[171] 黄春华, 朱本占. 碳中心苯醌自由基的捕获,分离及结构鉴定. 第五届全国环境化学大会会议论文集null. 2008, 28-, http://ir.rcees.ac.cn/handle/311016/5800.
[172] Zhu, BenZhan, Mao, Li. A Novel Hydroxyl Radical-Dependent Production of Chemiluminescence by Halogenated Quinones and Hydrogen Peroxide. FREE RADICAL BIOLOGY AND MEDICINEnull. 2008, 45: S65-S65, https://www.webofscience.com/wos/woscc/full-record/WOS:000260867900183.
[173] 张丹, 朱本占. 秦皮乙素可保护铁引起的细胞毒性. 第五届全国环境化学大会会议论文集null. 2008, 581-, http://ir.rcees.ac.cn/handle/311016/5862.
[174] Zhu, BenZhan, Zhang, YingNan. A Novel Mechanism of Protection by Penicillamine Against the Cytotoxicity Induced by Tetrachlorohydroquinone: Scavenging of the Reactive Tetrachlorosemiquinone Radical and the for Mation of the Less Reactive Penicillamine Thiol Radical. FREE RADICAL BIOLOGY AND MEDICINEnull. 2008, 45: S26-S26, https://www.webofscience.com/wos/woscc/full-record/WOS:000260867900066.
[175] 朱本占, 夏海英. 紫外-可见分光光度法简易检测“非金属依赖型”HO.生成的方法研究. 第五届全国环境化学大会会议论文集null. 2008, 482-483, http://ir.rcees.ac.cn/handle/311016/5861.
[176] 吴庆龙, 谢平, 杨柳燕, 高光, 刘正文, 潘纲, 朱本占. 湖泊蓝藻水华生态灾害形成机理及防治的基础研究. 地球科学进展[J]. 2008, 23(11): 1115-1123, http://lib.cqvip.com/Qikan/Article/Detail?id=28729052.
[177] Zhu, BenZhan, Shan, GuoQiang, Kalyanaraman, Balaraman. The ESR Detection of a Novel Carbon-Centered Quinone Radical and Characterization of Two Major Reaction Products Between Chlorinated Benzoquinone and t-Buooh. FREE RADICAL BIOLOGY AND MEDICINEnull. 2008, 45: S66-S66, https://www.webofscience.com/wos/woscc/full-record/WOS:000260867900184.
[178] 覃浩, 朱本占. 不依赖金属离子的脂质过氧化氢生成自由基机理研究. 第五届全国环境化学大会会议论文集null. 2008, 58-, http://ir.rcees.ac.cn/handle/311016/5885.
[179] 朱俊歌, 朱本占. 异羟肟酸催化四氯苯醌降解的反应机理研究. 第五届全国环境化学大会会议论文集null. 2008, 337-, http://ir.rcees.ac.cn/handle/311016/5856.
[180] 毛莉, 朱本占. 依赖于羟基自由基的四氯苯醌/过氧化氢体系的二次发光机理研究. 第五届全国环境化学大会会议论文集null. 2008, 51-, http://ir.rcees.ac.cn/handle/311016/5874.
[181] 范瑞梅, 朱本占. 镉的细胞毒性修复的初步研究. 第五届全国环境化学大会会议论文集null. 2008, 497-, http://ir.rcees.ac.cn/handle/311016/5852.
[182] Zhu, BenZhan, Zhao, HongTao, Kalyanaraman, Balaraman, Liu, Jun, Shan, GuoQiang, Du, YuGuo, Frei, Balz. Mechanism of metal-independent decomposition of organic hydroperoxides and formation of alkoxyl radicals by halogenated quinones. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2007, 104(10): 3698-3702, http://www.irgrid.ac.cn/handle/1471x/978958.
[183] Zhu, BenZhan, Kalyanaraman, Balaraman, Jiang, GuiBin. Molecular mechanism for metal-independent production of hydroxyl radicals by hydrogen peroxide and halogenated quinones. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2007, 104(45): 17575-17578, http://www.irgrid.ac.cn/handle/1471x/978964.
[184] Zhu, BenZhan. A novel molecular mechanism for metal-independent production of hydroxyl radicals by hydrogen peroxide and halogenated quinones. FREE RADICAL BIOLOGY AND MEDICINEnull. 2007, 43: S19-S20, https://www.webofscience.com/wos/woscc/full-record/WOS:000250835900050.
[185] Zhu, BenZhan. Metal-independent decomposition of organic hydroperoxides and formation of alkoxyl radicals by halogenated quinones: What is the underlying molecular mechanism?. FREE RADICAL BIOLOGY AND MEDICINEnull. 2007, 43: S20-S20, https://www.webofscience.com/wos/woscc/full-record/WOS:000250835900051.
[186] Dan Xu, ChunHua Huang, Li Qin, LinNa Xie, Li Mao, Jie Shao, Balaraman Kalyanaraman, BenZhan Zhu. TEMPORARY REMOVAL: An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids. FREE RADICAL BIOLOGY AND MEDICINE. http://dx.doi.org/10.1016/j.freeradbiomed.2019.07.009.

科研活动

   
科研项目
( 1 ) 大中型浅水湖泊蓝藻水华暴发机理研究, 主持, 国家级, 2008-01--2012-12
( 2 ) 环境化学, 主持, 国家级, 2010-01--2013-12
( 3 ) 不依赖金属离子存在型羟基自由基的生成及DNA损伤机理的研究, 主持, 国家级, 2008-01--2010-12
( 4 ) 有机与无机木材保护剂协同毒性作用机理的研究, 主持, 国家级, 2009-01--2011-12
( 5 ) 持久性有毒污染物的形态、环境过程与毒理效应, 参与, 国家级, 2008-01--2012-12
( 6 ) 持久性有机污染物的累积代谢及其与生物分子的相互作用, 主持, 国家级, 2009-01--2012-12
( 7 ) 有机农药与含铜、锌无机农药的协同毒性作用机理研究, 主持, 国家级, 2013-01--2017-12
( 8 ) 自由基化学, 主持, 部委级, 2006-06--2010-05
( 9 ) 污染物引发的自由基产生与生物损伤, 主持, 部委级, 2014-07--2019-07
( 10 ) 高级氧化过程中卤代芳烃产生化学发光的分子机制及应用研究, 主持, 国家级, 2015-01--2018-12
( 11 ) 持久性有毒污染物的环境过程与毒理效应, 主持, 国家级, 2014-01--2016-12
参与会议
(1)Redirecting Ru(II)-DPPZ Complex into Nucleus for Enantioselective Live-Cell DNA-Imaging and Photosensitizing via Simple 'Yin-Yang' Ion-Pairing   2016-07-26
(2)"Mechanism of Halogenated Quinone-mediated Free Radical Production and DNA Damage"   自由基专业委员会会议   朱本占   2015-08-13
(3)Delivering the DNA ‘Light-switching’ Ru(II) Complexes into Live-cell Nucleus via Ion-Pairing   15’分子探针与荧光成像国际研讨会   朱本占   2015-07-16
(4)"Mechanism of Free Radical-induced Oxidative DNA Damage/Adduct Formation and a Novel Fluorescent DNA Probe in Live Cells"   第二届活性氧生物学效应学术会议   朱本占   2015-03-10
(5)Molecular Mechanisms for Novel Free Radical Reactions, DNA Damage and Antioxidant Protection   朱本占   2014-11-14
(6)新型氧自由基诱导DNA氧化损伤的机理研究   中国环境诱变剂学会第16次学术大会   朱本占   2014-11-06
(7)新型自由基反应及DNA损伤的分子机理(口头报告)   2014年全国电子顺磁共振波谱学学术研讨会   朱本占   2014-09-11
(8)Hydroxyl radical-dependent chemiluminescence emmision during advanced oxidation of halogenated aromatic compounds   朱本占   2013-10-23
(9)The first purification and unequivocal characterization of an unusual carbon-centered quinone ketoxy radical adduct   朱本占   2012-11-13
(10)Unprecedented hydroxyl radical-dependent two-step chemiluminescence production by polyhalogenated quinoid carcinogens and H2O2   朱本占   2012-10-25
(11)From Free Radicals to Lossen Rearrangement, then Back to Free Radicals   朱本占   2012-10-11
(12)Generation and accumulation of cellular 5-hydroxymethylcytosine by redox-active quinines   朱本占   2012-09-18
(13)Mechanism of synergistic toxicity between organic and inorganic environmental pollutants   朱本占   2011-11-01
(14)Detection and Identification of a Novel Quinone Ketoxy Radical Produced by Metal-independent Decomposition of Hydroperoxides by Halogenated Quinones   Ben-zhan Zhu   2010-05-04
(15)Detection and Identification of a Novel Quinone Ketoxy Radical Produced by Metal-independent Decomposition of Hydroperoxides by Halogenated Quinones   Ben-zhan Zhu   2008-10-23
(16)Molecular Mechanism for metal-independent production of hydroxyl radicals by hydrogen peroxide and halogenated quinones   Ben-zhan Zhu   2007-07-01

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