General

Sijin Liu, Tuor of PHD students

Email: sjliu@rcees.ac.cn

Address: Shuangqing Road​ 18, Haidian District, Beijing city, China

Postalcode: 100085

Research Areas

Environmental medicine and Environmental toxicology, main contents: (1) The molecular mechanisms of environmental pollutants on blood cell damage. (2) Environment of oncology and the mechanism of tumor progression. (3) Biological safety of artificial nanomaterials.

Education

2001.09-2004.07 ​ Institute of Genetics and Developmental Biology, Chinese Academy of Sciences

Experience

   
Work Experience

2008.02-2009.08  Lecturer, Tufts university school of medicine, the United States

2007.07-2008.01   Research assistant, The Harvard University school of medicine

2004.08-2007.06   Postdoctoral, Massachusetts institute of technology (MIT), the United States

Teaching Experience

1. The application of modern biotechnology in environmental health research.

2. Research progression of environmental pollution and hazard.

Publications

   
Papers

1. Ma, J., Liu, R., Wang, X., Liu, Q., Chen, Y., Valle, RP., Zuo, YY., Xia, T.*, Liu, S.* (2015) Crucial Role of Lateral Size for Graphene Oxide in Activating Macrophages and Stimulating Pro-inflammatory Responses in Cells and Animals. ACS Nano. 9:10498-515.

2. Qian, Y., Zhang, J., Hu, Q., Xu, M., Chen, Y., Hu, G., Zhao, M.*, Liu, S.* (2015) Silver nanoparticle-induced hemoglobin decrease involves alteration of histone 3 methylation status. Biomaterials. 70:12-22.

3. Wang, Z., Xia, T.*, Liu, S.* (2015) Mechanisms of nanosilver-induced toxicological effects: more attention should be paid to its sublethal effects. Nanoscale. 7:7470-81.

4. Chen, Y., Zhang, Z., Yang, K., Du, J., Xu, Y.*, Liu, S.* (2015). Myeloid zinc finger 1 (MZF-1) suppresses prostate tumor growth through enforcing ferroportin-conducted iron egress. Oncogene. 34:3839-47.

5. Chen, Y., Wang, Z., Xu, M., Wang, X., Liu, R., Liu, Q., Zhang, Z., Xia, T., Zhao, J., Jiang, G., Xu, Y.*,Liu, S.* (2014). Nanosilver incurs an adaptive shunt of energy metabolism mode to glycolysis in tumor and nontumor cells. ACS Nano. 8:5813-25.

6. Zhang, C., Zhang, S., Zhang, Z., He, J., Xu, Y.*, Liu, S.* (2014) ROCK has a crucial role in regulating prostate tumor growth through interaction with c-Myc. Oncogene. 33:5582-91.

7. Qu, G., Liu, S.*, Zhang, S., Wang, L., Wang,X., Sun, B., Yin, N., Gao, X., Xia,T., Chen, J.J.,  Jiang,G. (2013). Graphene Oxide Induces Toll-like Receptor 4 (TLR4)-Dependent Necrosis in Macrophages. ACS Nano. 7:5732-45.

8. Wang, Z., Liu, S.*, Ma, J., Qu, G., Wang, X., Yu, S., He, J., Liu, J., Xia, T., Jiang, G. (2013). Silver Nanoparticles Induced RNA Polymerase-Silver Binding and RNA Transcription Inhibition in Erythroid Progenitor Cells. ACS Nano. 7: 4171-86.

9. Qu, G., Zhang, C., Yuan, L., He, J., Wang, Z., Wang, L., Liu, S.*, and Jiang, G. (2012). Quantum Dots Impair Macrophagic Morphology and the Ability of Phagocytosis by Inhibiting the Rho-Associated Kinase Signaling. Nanoscale. 4: 2239-44.

10. Suragani, R.N., Zachariah, R.S., Velazquez, J.G., Liu, S., Sun, C.W., Townes, T.M., and Chen, J.J.* (2012) Heme-regulated eIF2alpha kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis.Blood. 119:5276-84.

11. Liu, S., Goldstein, R.H., Scepansky, E.M., and Rosenblatt, M.* (2009). Inhibition of Rho-Associated Kinase Signaling Prevents Breast Cancer Metastasis to Human Bone. Cancer Res. 69: 8742-51.

12. Liu, S., Suragani, R., Wang, F., Han, A., Zhao, W., Andrews, N.C., and Chen, J.J.* (2007). The Function of Heme-Regulated eIF2-alpha Kinase in Murine Iron Homeostasis and Macrophage Maturation. J Clin Invest. 117: 3296-305.

Research Interests

Environmental medicine and Environmental toxicology

Students

已指导学生

张书平  博士研究生  083001-环境科学  

王立新  博士研究生  083001-环境科学  

王哲  博士研究生  083001-环境科学  

王雷  硕士研究生  430130-环境工程  

王小岩  博士研究生  083001-环境科学  

郭文丽  博士研究生  083001-环境科学  

刘静  博士研究生  083001-环境科学  

张洁  博士研究生  083001-环境科学  

高婕  硕士研究生  083001-环境科学  

马娟  博士研究生  083001-环境科学  

吴亚坤  博士研究生  083001-环境科学  

陈禹男  硕士研究生  077601-环境科学  

尹春阳  博士研究生  070303-有机化学  

陈永久  博士研究生  083001-环境科学  

汪顺浩  博士研究生  070303-有机化学  

申心铭  硕士研究生  085238-生物工程  

任泉仲  硕士研究生  077601-环境科学  

现指导学生

杨秋源  博士研究生  083001-环境科学  

刘伟  博士研究生  083001-环境科学  

闫旭  博士研究生  083001-环境科学  

冯文雅  博士研究生  070303-有机化学  

王瑞霞  博士研究生  083001-环境科学  

丘嘉煌  博士研究生  083001-环境科学  

徐立宁  博士研究生  083001-环境科学  

陈誉才  硕士研究生  086000-生物与医药  

董政  博士研究生  083001-环境科学